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Haptoglobin Phenotype, Vitamin E and High-density Lipoprotein (HDL) Function in Type 1 Diabetes
Sponsor: University of Pittsburgh
Summary
The purpose of the study is to determine whether the function of the good cholesterol (HDL cholesterol) as well as its subfractions (via NMR spectroscopy) is altered among people with type 1 diabetes and a variation in the Haptoglobin gene and to evaluate whether vitamin E supplements may improve this function.
Official title: Pilot and Feasibility Study for a Pharmacogenomic Trial in Type 1 Diabetes
Key Details
Gender
All
Age Range
30 Years - Any
Study Type
INTERVENTIONAL
Enrollment
87
Start Date
2010-02
Completion Date
2013-12
Last Updated
2026-11-02
Healthy Volunteers
No
Conditions
Interventions
Vitamin E
Daily administration of 400 IU natural d-alpha tocopherol acetate for 8 weeks
Dummy pills
Daily placebo administration for 8 weeks
Locations (1)
University of Pittsburgh Diabetes and Lipid Research Clinic
Pittsburgh, Pennsylvania, United States