Clinical Research Directory
Browse clinical research sites, groups, and studies.
Nitric Oxide-mediated Cardioprotection During Cardiac Surgery With Cardiopulmonary Bypass
Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences
Summary
This prospective randomized study elucidates the effects of exogenous nitric oxide delivered to the extracorporeal circulation circuit for cardioprotection against ischemia-reperfusion injury during coronary artery bypass graft surgery with cardiopulmonary bypass.
Key Details
Gender
All
Age Range
56 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2015-05-15
Completion Date
2016-11-30
Last Updated
2026-10-21
Healthy Volunteers
No
Conditions
Interventions
Nitric Oxide
40 ppm of exogenous gaseous nitric oxide is supplied directly to the oxygenator in the cardiopulmonary bypass circuit during coronary artery bypass grafting.
Standard CPB
Standard protocol of delivery of air gas mixture to the cardiopulmonary bypass circuit