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A Phase 1 Trial of OPB-111077 in Combination With Bendamustine and Rituximab in Patients With r/r DLBCL
Sponsor: Otsuka Pharmaceutical Co., Ltd.
Summary
To investigate the tolerability and safety of OPB-111077 in combination with bendamustine and rituximab in patients with r/r DLBCL.
Official title: A Phase 1, Multi-center, Open-label, Uncontrolled, Dose-escalation Trial to Evaluate the Safety of OPB-111077 in Combination With Bendamustine and Rituximab in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)
Key Details
Gender
All
Age Range
20 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
36
Start Date
2019-11-22
Completion Date
2026-01-19
Last Updated
2026-04-08
Healthy Volunteers
No
Interventions
OPB-111077
OPB-111077+bendamustine
OPB-111077
OPB-111077+rituximab+bendamustine
Locations (1)
Yamagata University Hospital
Yamagata, Japan