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COMPLETED
NCT04049825
PHASE1

A Phase 1 Trial of OPB-111077 in Combination With Bendamustine and Rituximab in Patients With r/r DLBCL

Sponsor: Otsuka Pharmaceutical Co., Ltd.

View on ClinicalTrials.gov

Summary

To investigate the tolerability and safety of OPB-111077 in combination with bendamustine and rituximab in patients with r/r DLBCL.

Official title: A Phase 1, Multi-center, Open-label, Uncontrolled, Dose-escalation Trial to Evaluate the Safety of OPB-111077 in Combination With Bendamustine and Rituximab in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Key Details

Gender

All

Age Range

20 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

36

Start Date

2019-11-22

Completion Date

2026-01-19

Last Updated

2026-04-08

Healthy Volunteers

No

Interventions

DRUG

OPB-111077

OPB-111077+bendamustine

DRUG

OPB-111077

OPB-111077+rituximab+bendamustine

Locations (1)

Yamagata University Hospital

Yamagata, Japan