Clinical Research Directory

Inclusion Criteria: * Age ≥ 18 years * T1DM (Diagnosis of diabetes before the age of 35 years and insulin use within 1 year of diagnosis) * Treatment with multiple daily insulin injections (MDI) or continuous subcutaneous insulin infusion (CSII) Exclusion Criteria: * Any cardiovascular disease within the last 3 months * NYHA stage 3 or 4 heart failure * Uncontrolled angina * Liver failure \[AST\>135 IU/L or ALT\>129IU/L (3 x the upper normal limit)\] • Kidney failure or GFR\<60 ml/min/1.73m2 * Gastrointestinal disease or gastroparesis * Prior diagnosis of cancer within 2 years * Other medication that affect glucose metabolism within the last 3 months (metformin, SGLT2, GLP-1 analogues, amylin analogues, systemic glucocorticosteroids) * Untreated or uncontrolled thyroid disease * Pregnancy or breastfeeding * Alcohol consumption \> 2-drinks per day or other substance abuse