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COMPLETED
NCT04393792
PHASE1

SINUS WASH Pilot Study in Adults Testing Positive for COVID-19

Sponsor: Hampshire Hospitals NHS Foundation Trust

View on ClinicalTrials.gov

Summary

COVID-19 is highly infectious and transmission of the virus is thought to be similar to that of influenza which can be transferred through droplets released when a person coughs, sneezes or talks. Studies have shown that nasal rinsing and mouth washes may be an important way to deliver treatments that could reduce the amount of a virus that is present in the nose and mouth. This also could mean that there is less virus available to pass on to others. We want to see if the use of nose rinses and mouth washes using Povidone-Iodine will reduce the the amount of virus in the nose and throat of people who have tested positive for COVID-19 disease and also reduce the spread of infection within their household.

Official title: Can a Sinus Rinse and Mouth Wash Reduce Viral Load in COVID-19 Positive Individuals and Their Co-residents?

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

58

Start Date

2020-05-05

Completion Date

2023-09-30

Last Updated

2026-10-21

Healthy Volunteers

No

Interventions

DRUG

Povidone-Iodine

0.23% three times daily (tds) for 3 days

DRUG

Normal saline

0.9% three times daily (tds) for 3 days

Locations (1)

Hampshire Hospitals NHS Foundation Trust

Basingstoke, Hampshire, United Kingdom