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Body Weight, Aspirin Dose and Pro-resolving Mediators
Sponsor: NYU Langone Health
Summary
This study employs a placebo-controlled randomized cross-over design to investigate the impact of body weight and aspirin dose on levels of specialized pro-resolving lipid mediators in blood and neutrophils.
Official title: DISCOVER: A Single-site Double-blind Placebo-controlled Randomized Mechanistic Crossover Trial to Assess the Influence of boDy weIght on aSpirin-triggered speCialized prO-resolVing mEdiatoRs
Key Details
Gender
All
Age Range
40 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
108
Start Date
2021-11-04
Completion Date
2025-01-29
Last Updated
2026-10-27
Healthy Volunteers
Yes
Conditions
Interventions
Aspirin 81mg
81mg oral capsule
Aspirin 325mg
325mg oral capsule
Locations (1)
NYU Langone Health
New York, New York, United States