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COMPLETED
NCT04786548
PHASE2

Neuroinflammation in Patients With OCD

Sponsor: New York State Psychiatric Institute

View on ClinicalTrials.gov

Summary

The goal of this study is to examine whether measurements of inflammation from brain scanning and blood tests can predict how much benefit patients with obsessive-compulsive disorder (OCD) will have from treatment with an anti-inflammatory medication, celecoxib, when adding to ongoing medication-based treatment for OCD.

Official title: A Precision Medicine Approach to OCD Treatment: Targeting Neuroinflammation

Key Details

Gender

All

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

18

Start Date

2021-04-01

Completion Date

2026-10-28

Last Updated

2026-10-30

Healthy Volunteers

No

Interventions

DRUG

Celecoxib

Patients will receive standardized pharmacotherapy with celecoxib 100mg twice daily for the first week, and will then, if well-tolerated, will be increased to 200mg twice daily for the next seven weeks.

Locations (1)

New York State Psychiatric Institute

New York, New York, United States