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Evaluation of Next-Generation Sequencing-based Metabarcoding Versus Culturing for Microbiological Assessment in Infectious Keratitis
Sponsor: Aarhus University Hospital
Summary
Infectious keratitis is a potential sight threatening condition. In conventional clinical practice culturing is performed in order to identify the causative microbial organism; however in recent years Next Generation Sequencing for the presence of ribosomal DNA from bacteria, fungi, or amoeba has become available. The present study aims to compare conventional culturing with Next Generation Sequencing for identifying microorganism causing keratitis.
Official title: Evaluation of Next-Generation Sequencing-based Metabarcoding Versus Culturing in Infectious Keratitis
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
57
Start Date
2021-12-09
Completion Date
2024-06-01
Last Updated
2026-10-28
Healthy Volunteers
No
Conditions
Interventions
Next generation sequencing
Evaluation of microbiological culturing versus next generation sequencing for ribosomal DNA
Locations (1)
Department of Ophthalmology, Aarhus University Hospital
Aarhus, Denmark