Clinical Research Directory
Browse clinical research sites, groups, and studies.
Hypoproteic Diet in Acromegaly
Sponsor: Azienda Ospedaliero Universitaria Maggiore della Carita
Summary
Since protein and AAs are master regulator of GH and IGF-I secretion, we hypothesized that a low protein diet could reduce GH and IGF-I levels in acromegalic patients in addition to conventional therapy. Furthermore, we aim to explore metabolomic, microbiota, and micro-vesicle fingerprints of GH hypersecretion during conventional therapy and after a low protein diet
Official title: Deciphering the Role of a Low Protein Diet in Disease Control in Acromegalic Patients
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2026-12-01
Completion Date
2029-03-01
Last Updated
2026-10-29
Healthy Volunteers
No
Conditions
Interventions
Usual clinical practice + hypoproteic diet
Diet will be composed by: * energy equal to daily energy expenditure (estimated by indirect calorimetry \* physical activity factor) * fats 28-35% * carbohydrates 50-60% * proteins 0,7-0,8g/kg of body weight 10-13% Diet will be given to the patient after the first visit and the study will start once the patient begins the diet.
Locations (1)
: Italy Pediatric Endocrine Service of AOU Maggiore della Carità of Novara; SCDU of Pediatrics, Department of Health Sciences, University of Eastern Piedmont
Novara, Italy, Italy