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COMPLETED
NCT05351515

Prevalence of Non-alcoholic Fatty Liver Disease Among Non-obese Obstructive Sleep Apnea by Using Transient Elastography

Sponsor: Chinese University of Hong Kong

View on ClinicalTrials.gov

Summary

Obstructive sleep apnea (OSA) and non-alcoholic fatty liver disease (NAFLD) are both common diseases related to metabolic diseases with potential cardiovascular consequences and liver complications respectively. Though studies show OSA may take part in the progression of hepatic steatosis, the independent contribution of OSA on liver fat accumulation is unknown. It is hypothesized that nocturnal intermittent hypoxia from OSA is the main driver of NAFLD in non-obese OSA patients. This study is to assess the effect of OSA on NAFLD in non-obese patients.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

OBSERVATIONAL

Enrollment

861

Start Date

2022-01-10

Completion Date

2026-07-31

Last Updated

2026-10-20

Healthy Volunteers

Yes

Locations (1)

Chinese University of Hong Kong

Hong Kong, Hong Kong, Hong Kong