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Metformin in Patients With Ulcerative Colitis Treated With Mesalamine
Sponsor: Tanta University
Summary
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease characterized by diffused inflammation of the colon and rectum mucosa, however, the exact underlying mechanisms of UC remain poorly understood.UC is strongly dependent on cellular immune reaction and exaggerated inflammatory response due to genetic, immune and environmental factors.
Official title: Clinical Study to Compare the Possible Efficacy of Metformin in Patients With Ulcerative Colitis Treated With Mesalamine
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2022-11-01
Completion Date
2023-12-01
Last Updated
2026-10-30
Healthy Volunteers
No
Conditions
Interventions
Metformin
metformin group will take mesalamine 1 gm three times daily plus metformin 500 mg two times daily
Locations (1)
Faculty of Medicine, Mansoura University
Al Mansurah, Egypt