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A Comparative Clinical Trial Evaluating the Effect and Safety of Tacrolimus Versus Hydrocortisone
Sponsor: Tanta University
Summary
One of the most frequent skin conditions is atopic dermatitis (AD), characterized by its pruritic inflammation effect. Where the prevalence of AD increased in the last three decades by two or three folds worldwide, especially in developed countries, AD is supposed to affect about 15% to 30% of children, and 2% to 10% of adults. This type of dermatitis is frequently linked to a family history of other atopic illnesses such as allergic rhinitis or asthma.
Official title: A Comparative Clinical Trial Evaluating the Effect and Safety of Tacrolimus Versus Hydrocortisone in Management of Atopic Dermatitis in Children
Key Details
Gender
All
Age Range
2 Years - 16 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2022-11-28
Completion Date
2023-08-20
Last Updated
2026-10-30
Healthy Volunteers
No
Conditions
Interventions
Tacrolimus ointment
tacrolimus is an immunosuppressive drug acting as an immunomodulator to assist manage acute flares and reducing the severity of future flares
Hydrocortisone 1% cream
Topical corticosteroids (TCS) are the cornerstone for the management of AD to which other treatments are compared.
Locations (1)
Tanta Unuversity
Tanta, Egypt