Clinical Research Directory

Inclusion Criteria: * 18 - 90 years old Chinese male subjects presented with male-LUTS for at least 4 weeks * The subjects are able to read and fully comprehend with the content of the questionnaires * The subjects are willing to give informed consent for the study Exclusion Criteria: * peak uroflow ≤4mL/sec; * post-void residual (PVR) ≥300 mL; * unable to give informed consent * need of clean intermittent self-catheterization / indwelling urethral catheterization at the time of enrolment; * Surgical treatment (e.g. TURP) of bladder outlet obstruction / symptomatic benign prostate enlargement (BPE) ≤ 3 months before entry into the study * clinical suspicion / presence of untreated urethral stricture and/or bladder neck stenosis, * clinical suspicion / presence of genitourinary cancer including active prostate cancer with ongoing surgical or radiation treatment, or the need of treatment, or bladder cancer, or persistent unexplained hematuria; * uncontrolled heart failure / diabetes mellitus(DM) / hypertension(HT); * neuropathic bladder; * Currently on dialysis or in consideration for dialysis due to end stage renal disease; * More than 3 urinary tract infections within the last 12 months; * Unstable dose of diuretic within the past 3 months; * Has an artificial urinary sphincter; * Impaired mental status; * male-LUTS due to urinary tract infections / chronic prostatitis / chronic pelvic pain