Clinical Research Directory
Browse clinical research sites, groups, and studies.
To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia
Sponsor: 89bio, Inc.
Summary
To determine the effect of Pegozafermin on fasting serum triglyceride levels in subjects with Severe Hypertriglyceridemia (TG ≥500 to ≤2000 mg/dL) after 26 weeks of treatment.
Official title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia (SHTG): The ENTRUST Study
Key Details
Gender
All
Age Range
22 Years - Any
Study Type
INTERVENTIONAL
Enrollment
369
Start Date
2023-06-15
Completion Date
2026-04-09
Last Updated
2026-07-07
Healthy Volunteers
No
Conditions
Interventions
Pegozafermin
Subcutaneous injection
Placebo
Subcutaneous injection
Locations (177)
89bio Clinical Study Site
Chandler, Arizona, United States
89bio Clinical Study Site
Peoria, Arizona, United States
89Bio Clinical Study Site
Tucson, Arizona, United States
89bio Clinical Study Site
Conway, Arkansas, United States
89bio Clinical Study Site
Jonesboro, Arkansas, United States
89bio Clinical Study Site
Little Rock, Arkansas, United States
89bio Clinical Trial Site
Huntington Park, California, United States
89Bio Clinical Study Site
Long Beach, California, United States
89bio Clinical Study Site
Los Angeles, California, United States
89bio Clinical Trial Site
Northridge, California, United States
89bio Clinical Trial Site
Panorama City, California, United States
89bio Clinical Study Site
Santa Ana, California, United States
89bio Clinical Trial Site
Santa Ana, California, United States
89bio Clinical Study Site
Thousand Oaks, California, United States
89Bio Clinical Study Site
Tustin, California, United States
89bio Clinical Study Site
Wheat Ridge, Colorado, United States
89bio Clinical Trial Site
Wheat Ridge, Colorado, United States
89bio Clinical Study Site
Bridgeport, Connecticut, United States
89Bio Clinical Study Site
Clearwater, Florida, United States
89bio Clinical Study Site
Clearwater, Florida, United States
89bio Clinical Study Site
Hialeah Gardens, Florida, United States
89Bio Clinical Study Site
Homestead, Florida, United States
89Bio Clinical Study Site
Miami Lakes, Florida, United States
89bio Clinical Study Site
Miramar, Florida, United States
89Bio Clinical Study Site
Orlando, Florida, United States
89bio Clinical Study Site
Panama City, Florida, United States
89bio Clinical Trial Site
Port Orange, Florida, United States
89Bio Clinical Study Site
Tampa, Florida, United States
89bio Clinical Study Site
Atlanta, Georgia, United States
89Bio Clinical Study Site
Columbus, Georgia, United States
89Bio Clinical Study Site
Lawrenceville, Georgia, United States
89Bio Clinical Study Site
Chicago, Illinois, United States
89bio Clinical Study Site
West Des Moines, Iowa, United States
89Bio Clinical Study Site
Wichita, Kansas, United States
89Bio Clinical Study Site
Marrero, Louisiana, United States
89bio Clinical Trial Site
Shreveport, Louisiana, United States
89Bio Clinical Study Site
Oxon Hill, Maryland, United States
89bio Clinical Study Site
Flint, Michigan, United States
89bio Clinical Trial Site
Kansas City, Missouri, United States
89bio Clinical Study Site
St Louis, Missouri, United States
89bio Clinical Study Site
Las Vegas, Nevada, United States
89bio Clinical Study Site
Las Vegas, Nevada, United States
89bio Clinical Study Sites
Sparta, New Jersey, United States
89bio Clinical Study Site
East Syracuse, New York, United States
89bio Clinical Trial Site
New Windsor, New York, United States
89bio Clinical Trial Site
New York, New York, United States
89Bio Clinical Study Site
North Massapequa, New York, United States
89bio Clinical Trial Site
Richmond Hill, New York, United States
89bio Clinical Trial Site
Syracuse, New York, United States
89Bio Clinical Study Site
Morganton, North Carolina, United States
89bio Clinical Study Site
Cincinnati, Ohio, United States
89bio Clinical Trial Site
Columbus, Ohio, United States
89bio Clinical Study Site
Middleburg Heights, Ohio, United States
89bio Clinical Study Site
Stow, Ohio, United States
89bio Clinical Study Site
Oklahoma City, Oklahoma, United States
89Bio Clinical Study Site
Eugene, Oregon, United States
89bio Clinical Study Site
Charleston, South Carolina, United States
89Bio Clinical Study Site
Chattanooga, Tennessee, United States
89bio Clinical Trial Site
Clarksville, Tennessee, United States
89bio Clinical Study Site
Tullahoma, Tennessee, United States
89bio Clinical Study Site
Amarillo, Texas, United States
89 Clinical Study Site
Austin, Texas, United States
89bio Clinical Study Site
Dallas, Texas, United States
89bio Clinical Study Site
Graham, Texas, United States
89bio Clinical Study Site
Houston, Texas, United States
89Bio Clinical Study Site
Lampasas, Texas, United States
89bio Clinical Study Site
Mansfield, Texas, United States
89bio Clinical Trial Site
San Antonio, Texas, United States
89bio Clinical Study Site
San Antonio, Texas, United States
89bio Clinical Study Site
Wichita Falls, Texas, United States
89bio Clinical Trial Site
Salt Lake City, Utah, United States
89Bio Clinical Study Site
Burke, Virginia, United States
89bio Clinical Trial Site
Richmond, Virginia, United States
89bio Clinical Study Site
Rosario, Santa Fe Province, Argentina
89bio Clinical Study Site
Buenos Aires, Argentina
89bio Clinical Study Site
Buenos Aires, Argentina
89bio Clinical Study Site
Buenos Aires, Argentina
89bio Clinical Study Site
Córdoba, Argentina
89bio Clinical Study Site
Córdoba, Argentina
89bio Clinical Study Site
Córdoba, Argentina
89bio Clinical Study Site
Córdoba, Argentina
89bio Clinical Study Site
Córdoba, Argentina
89bio Clinical Study Site
Mendoza, Argentina
89bio Clinical Study Site
Rosario, Argentina
89bio Clinical Study Site
San Miguel de Tucumán, Argentina
89bio Clinical Study Site
Viedma, Argentina
89bio Clinical Study Site
Graz, Austria
89bio Clinical Trial Site
Vienna, Austria
89bio Clinical Trial Site
Vienna, Austria
89bio Clinical Study Site
Edegem, Belgium
89bio Clinical Study Site
Ghent, Belgium
89bio Clinical Study Site
Haine-Saint-Paul, Belgium
89bio Clinical Study Site
Yvoir, Belgium
89bio Clinical Trial Site
Botevgrad, Bulgaria
89bio Clinical Study Site
Dimitrovgrad, Bulgaria
89bio Clinical Trial Site
Plovdiv, Bulgaria
89bio Clinical Study Site
Sliven, Bulgaria
89bio Clinical Trial Site
Sliven, Bulgaria
89bio Clinical Trial Site
Sofia, Bulgaria
89bio Clinical Study Site
Sofia, Bulgaria