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A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)
Sponsor: Amgen
Summary
The primary objective of this study is to describe the long-term safety and tolerability of rocatinlimab in participants with moderate-to-severe AD.
Official title: A Phase 3, Multicenter, Double-blind Maintenance Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-ASCEND)
Key Details
Gender
All
Age Range
12 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
2621
Start Date
2023-05-31
Completion Date
2026-07-01
Last Updated
2026-07-16
Healthy Volunteers
No
Conditions
Interventions
Rocatinlimab
Subcutaneous (SC) injection
Placebo
SC injection
Locations (547)
Cahaba Dermatology and Skin Health Center
Birmingham, Alabama, United States
Medical Dermatology Specialists
Phoenix, Arizona, United States
Alliance Dermatology and Mohs Center
Phoenix, Arizona, United States
Affiliated Dermatology
Scottsdale, Arizona, United States
Scottsdale Clinical Trials
Scottsdale, Arizona, United States
Dermatology Trial Associates
Bryant, Arkansas, United States
Burke Pharmaceutical Research
Hot Springs, Arkansas, United States
Arkansas Research Trials, LLC
North Little Rock, Arkansas, United States
Kern Research Inc
Bakersfield, California, United States
Hope Clinical Research LLC
Canoga Park, California, United States
West Coast Research LLC
Dublin, California, United States
California Dermatology and Clinical Research Institute
Encinitas, California, United States
First OC Dermatology
Fountain Valley, California, United States
Antelope Valley Clinical Trials
Lancaster, California, United States
Chemidox Clinical Trials Incorporated
Lancaster, California, United States
Long Beach Research Institute
Long Beach, California, United States
University of California Los Angeles
Los Angeles, California, United States
Dermatology Research Associates
Los Angeles, California, United States
Wallace Medical Group Inc
Los Angeles, California, United States
Northridge Clinical Trials
Northridge, California, United States
University of California Irvine
Orange, California, United States
Havana Research Institute Inc
Pasadena, California, United States
Integrative Skin Science and Research
Sacramento, California, United States
University of California at Davis Medical Center
Sacramento, California, United States
Kaiser Permanente South Sacramento Medical Center
Sacramento, California, United States
Alliance Clinical Research
San Diego, California, United States
Kaiser Permanente Medical Center - Oakland
San Francisco, California, United States
Kaiser Permanente Medical Center - San Francisco
San Francisco, California, United States
Wolverine Clinical Trials
Santa Ana, California, United States
Clinical Science Institute
Santa Monica, California, United States
IMMUNOe Research Centers
Centennial, Colorado, United States
Skin Care Research Incorporated
Boca Raton, Florida, United States
Renaissance Research and Medical Group
Cape Coral, Florida, United States
Driven Research LLC
Coral Gables, Florida, United States
Corazon United States of America, LLC doing business as Life Clinical Trials
Coral Springs, Florida, United States
D and H Doral Research Centers
Doral, Florida, United States
Saint Jude Clinical Research
Doral, Florida, United States
Direct Helpers Research Center
Hialeah, Florida, United States
Global Research Solutions
Homestead, Florida, United States
Nexus Clinical Research
Homestead, Florida, United States
Glick Skin Institute
Margate, Florida, United States
ara Professionals Limited Liability Corporation
Miami, Florida, United States
Gold Coast Health Research Center
Miami, Florida, United States
Miami Clinical Research
Miami, Florida, United States
Healthy Life Research
Miami, Florida, United States
Anchor Medical Research
Miami, Florida, United States
Meridian International Research
Miami Gardens, Florida, United States
Savin Medical Group LLC
Miami Lakes, Florida, United States
Clinical Associates of Orlando Limited Liability Company
Orlando, Florida, United States
Innovation Medical Research Center Inc
Palmetto Bay, Florida, United States
University of South Florida
Tampa, Florida, United States
Olympian Clinical Research - Tampa
Tampa, Florida, United States
Atlanta Dermatology, Vein and Research Center, PC
Alpharetta, Georgia, United States
First Georgia Physicians Group
Fayetteville, Georgia, United States
Advanced Medical Research PC
Sandy Springs, Georgia, United States
Treasure Valley Medical Research
Boise, Idaho, United States
DeNova Research
Chicago, Illinois, United States
Sneeze, Wheeze, and Itch Associates, LLC
Normal, Illinois, United States
Endeavor Health Clinical Trials Center
Skokie, Illinois, United States
Dundee Dermatology
West Dundee, Illinois, United States
DS Research
Clarksville, Indiana, United States
Dawes Fretzin Clinical Research Group, LLC
Indianapolis, Indiana, United States
Southern Indiana Clinical Trials
New Albany, Indiana, United States
The Indiana Clinical Trials Center PC
Plainfield, Indiana, United States
Options Research Group LLC
West Lafayette, Indiana, United States
Dermatology and Skin Cancer Center Leawood
Leawood, Kansas, United States
DS Research
Louisville, Kentucky, United States
Kentucky Advanced Medical Research LLC
Murray, Kentucky, United States
Foxhall Research Center
Chevy Chase, Maryland, United States
Institute for Asthma and Allergy
Chevy Chase, Maryland, United States
Continental Clinical Solutions, LLC
Towson, Maryland, United States
MetroBoston Clinical Partners
Brighton, Massachusetts, United States
University of Michigan
Ann Arbor, Michigan, United States
Henry Ford Medical Center - New Center One
Detroit, Michigan, United States
Onyx Clinical Research
Flint, Michigan, United States
Revival Research Institute LLC
Troy, Michigan, United States
Somerset Skin Centre
Troy, Michigan, United States
Dermatology and Skin Cancer Center of Lees Summit
Lee's Summit, Missouri, United States
Saint Louis University
St Louis, Missouri, United States
Somnos Clinical Research
Lincoln, Nebraska, United States
Jubilee Clinical Research Inc
Las Vegas, Nevada, United States
Excel Clinical Research
Las Vegas, Nevada, United States
Las Vegas Clinical Trials
North Las Vegas, Nevada, United States
Skin Cancer and Dermatology Institute
Reno, Nevada, United States
Albuquerque Clinical Trials Incorporated
Albuquerque, New Mexico, United States
Forest Hills Dermatology Group
Kew Gardens, New York, United States
Icahn School of Medicine at Mount Sinai
New York, New York, United States
Sadick Research Group
New York, New York, United States
OptiSkin Medical
New York, New York, United States
Chear Center LLC
The Bronx, New York, United States
DJL Clinical Research PLLC
Charlotte, North Carolina, United States
Wilmington Dermatology Center
Wilmington, North Carolina, United States
Accellacare of Wilmington
Wilmington, North Carolina, United States
The Skin Surgery Center for Clinical Research
Winston-Salem, North Carolina, United States
Bexley Dermatology Research
Bexley, Ohio, United States
Bernstein Clinical Research Center LLC
Cincinnati, Ohio, United States
The Ohio State University
Gahanna, Ohio, United States
Apex Clinical Research Center LLC
Mayfield Heights, Ohio, United States
Dermatologist of Central States Clinical Research - Springfield
Springfield, Ohio, United States
Unity Clinical Research
Oklahoma City, Oklahoma, United States