Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus
Sponsor: AstraZeneca
Summary
This study aims to evaluate the efficacy and safety of subcutaneous (SC) anifrolumab versus placebo in adult participants with chronic and/or subacute cutaneous lupus erythematosus (CLE).
Official title: A Multicenter, Randomized, Double Blind, Placebo Controlled, Phase III Study to Evaluate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus Who Are Refractory and/or Intolerant to Antimalarial Therapy.
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
339
Start Date
2024-06-29
Completion Date
2027-08-10
Last Updated
2026-07-29
Healthy Volunteers
No
Conditions
Interventions
Anifrolumab
Anifrolumab will be provided as a solution for injection in accessorized pre-filled syringe (aPFS).
Placebo
Matching placebo solution for injection in aPFS.
Locations (188)
Research Site
Phoenix, Arizona, United States
Research Site
Covina, California, United States
Research Site
La Jolla, California, United States
Research Site
Los Angeles, California, United States
Research Site
Los Angeles, California, United States
Research Site
Orange, California, United States
Research Site
San Francisco, California, United States
Research Site
Aurora, Colorado, United States
Research Site
New Haven, Connecticut, United States
Research Site
Washington D.C., District of Columbia, United States
Research Site
Fort Lauderdale, Florida, United States
Research Site
Miami, Florida, United States
Research Site
Plantation, Florida, United States
Research Site
Chicago, Illinois, United States
Research Site
Chicago, Illinois, United States
Research Site
Indianapolis, Indiana, United States
Research Site
Baltimore, Maryland, United States
Research Site
Boston, Massachusetts, United States
Research Site
Boston, Massachusetts, United States
Research Site
Ann Arbor, Michigan, United States
Research Site
Bloomfield Hills, Michigan, United States
Research Site
Rochester, Minnesota, United States
Research Site
Omaha, Nebraska, United States
Research Site
New York, New York, United States
Research Site
Rochester, New York, United States
Research Site
Charlotte, North Carolina, United States
Research Site
Statesville, North Carolina, United States
Research Site
Cleveland, Ohio, United States
Research Site
Portland, Oregon, United States
Research Site
Providence, Rhode Island, United States
Research Site
Charleston, South Carolina, United States
Research Site
Dallas, Texas, United States
Research Site
Charlottesville, Virginia, United States
Research Site
Roanoke, Virginia, United States
Research Site
Ciudad de Buenos Aires, Argentina
Research Site
Córdoba, Argentina
Research Site
Córdoba, Argentina
Research Site
Quilmes, Argentina
Research Site
San Miguel, Argentina
Research Site
Kogarah, Australia
Research Site
Melbourne, Australia
Research Site
Mitcham, Australia
Research Site
Westmead, Australia
Research Site
Woolloongabba, Australia
Research Site
Graz, Austria
Research Site
Innsbruck, Austria
Research Site
Linz, Austria
Research Site
Vienna, Austria
Research Site
Belo Horizonte, Brazil
Research Site
Porto Alegre, Brazil
Research Site
Rio de Janeiro, Brazil
Research Site
Salvador, Brazil
Research Site
São Paulo, Brazil
Research Site
Sofia, Bulgaria
Research Site
Sofia, Bulgaria
Research Site
Sofia, Bulgaria
Research Site
Vancouver, British Columbia, Canada
Research Site
Hamilton, Ontario, Canada
Research Site
Toronto, Ontario, Canada
Research Site
Osorno, Chile
Research Site
Santiago, Chile
Research Site
Santiago, Chile
Research Site
Changchun, China
Research Site
Changsha, China
Research Site
Chengdu, China
Research Site
Chongqing, China
Research Site
Dongguan, China
Research Site
Guangzhou, China
Research Site
Heilongjiang, China
Research Site
Jinan, China
Research Site
Shanghai, China
Research Site
Shanghai, China
Research Site
Shenzhen, China
Research Site
Shenzhen, China
Research Site
Shenzhen, China
Research Site
Ürümqi, China
Research Site
Zhuzhou, China
Research Site
Barranquilla, Colombia
Research Site
Bogotá, Colombia
Research Site
Aarhus, Denmark
Research Site
Copenhagen, Denmark
Research Site
Bois-Guillaume, France
Research Site
Dijon, France
Research Site
Lyon, France
Research Site
Montivilliers, France
Research Site
Nantes, France
Research Site
Paris, France
Research Site
Paris, France
Research Site
Paris, France
Research Site
Paris, France
Research Site
Poitiers, France
Research Site
Toulouse, France
Research Site
Berlin, Germany
Research Site
Bochum, Germany
Research Site
Dresden, Germany
Research Site
Erlangen, Germany
Research Site
Essen, Germany
Research Site
Freiburg im Breisgau, Germany
Research Site
Hanover, Germany
Research Site
Kiel, Germany