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A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa
Sponsor: Incyte Corporation
Summary
The purpose of this study is to evaluate long-term safety and efficacy of povorcitinib in participants with moderate to severe hidradenitis suppurativa who completed the 54 weeks of study treatment within the originating parent Phase 3 studies (INCB 54707-301 \[NCT05620823\] or INCB 54707-302 \[NCT05620836\]).
Official title: A Phase 3, Double-Blind Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
617
Start Date
2024-01-30
Completion Date
2026-12-26
Last Updated
2026-08-25
Healthy Volunteers
No
Conditions
Interventions
Povorcitinib
Oral; Tablet
Locations (165)
Investigative Site US303
Phoenix, Arizona, United States
Investigative Site US240
Scottsdale, Arizona, United States
Investigative Site US307
Fort Smith, Arkansas, United States
Investigative Site US214
Rogers, Arkansas, United States
Investigative Site US315
Laguna Niguel, California, United States
Investigative Site US223
Los Angeles, California, United States
Investigative Site US222
Oakland, California, United States
Investigative Site US226
San Diego, California, United States
Investigative Site US309
Clearwater, Florida, United States
Investigative Site US317
Hialeah, Florida, United States
Investigative Site US306
Hollywood, Florida, United States
Investigative Site US320
Hollywood, Florida, United States
Investigative Site US316
Maitland, Florida, United States
Investigative Site US227
Margate, Florida, United States
Investigative Site US204
Miami, Florida, United States
Investigative Site US236
Miami, Florida, United States
Investigative Site US321
North Miami Beach, Florida, United States
Investigative Site US200
Ocala, Florida, United States
Investigative Site US228
Tampa, Florida, United States
Investigative Site US201
Tampa, Florida, United States
Investigative Site US311
Marietta, Georgia, United States
Investigative Site US220
West Dundee, Illinois, United States
Investigative Site US206
Indianapolis, Indiana, United States
Investigative Site US337
Indianapolis, Indiana, United States
Investigative Site US341
Bowling Green, Kentucky, United States
Investigative Site US209
Louisville, Kentucky, United States
Investigative Site US305
Baton Rouge, Louisiana, United States
Investigative Site US207
Metairie, Louisiana, United States
Investigative Site US229
New Orleans, Louisiana, United States
Investigative Site US224
Baltimore, Maryland, United States
Investigative Site US325
Marriottsville, Maryland, United States
Investigative Site US225
Boston, Massachusetts, United States
Investigative Site US304
Boston, Massachusetts, United States
Investigative Site US310
Brighton, Massachusetts, United States
Investigative Site US221
Quincy, Massachusetts, United States
Investigative Site US213
Fort Gratiot, Michigan, United States
Investigative Site US217
Waterford, Michigan, United States
Investigative Site US212
Minneapolis, Minnesota, United States
Investigative Site US302
St Louis, Missouri, United States
Investigative Site US318
Portsmouth, New Hampshire, United States
Investigative Site US230
East Windsor, New Jersey, United States
Investigative Site US324
Kew Gardens, New York, United States
Investigative Site US202
New York, New York, United States
Investigative Site US210
Rochester, New York, United States
Investigative Site US205
Chapel Hill, North Carolina, United States
Investigative Site US215
Bexley, Ohio, United States
Investigative Site US339
Bexley, Ohio, United States
Investigative Site US330
Boardman, Ohio, United States
Investigative Site US314
Cincinnati, Ohio, United States
Investigative Site US312
Cleveland, Ohio, United States
Investigative Site US203
Gahanna, Ohio, United States
Investigative Site US301
Portland, Oregon, United States
Investigative Site US232
Murfreesboro, Tennessee, United States
Investigative Site US235
Arlington, Texas, United States
Investigative Site US218
Bellaire, Texas, United States
Investigative Site US340
Bellaire, Texas, United States
Investigative Site US238
Pflugerville, Texas, United States
Investigative Site US300
Plano, Texas, United States
Investigative Site US234
San Antonio, Texas, United States
Investigative Site US313
Norfolk, Virginia, United States
Investigative Site US308
Spokane, Washington, United States
Investigative Site AU203
Charlestown, New South Wales, Australia
Investigative Site AU205
Kogarah, New South Wales, Australia
Investigative Site AU200
Liverpool, New South Wales, Australia
Investigative Site AU206
Woolloongabba, Queensland, Australia
Investigative Site AU207
Woolloongabba, Queensland, Australia
Investigative Site AU201
Carlton, Victoria, Australia
Investigative Site AU204
Melbourne, Victoria, Australia
Investigative Site AT306
Inssbruck, Austria
Investigative Site AT305
Vienna, Austria
Investigative Site BE300
Brussels, Belgium
Investigative Site BE301
Ghent, Belgium
Investigative Site BE302
Liège, Belgium
Investigative Site BG203
Sofia, Bulgaria
Investigative Site BG202
Sofia, Bulgaria
Investigative Site BG200
Sofia, Bulgaria
Investigative Site BG204
Sofia, Bulgaria
Investigative Site BG201
Stara Zagora, Bulgaria
Investigative Site CA202
Calgary, Alberta, Canada
Investigative Site CA204
Edmonton, Alberta, Canada
Investigative Site CA200
Surrey, British Columbia, Canada
Investigative Site CA301
Winnipeg, Manitoba, Canada
Investigative Site CA205
Fredericton, New Brunswick, Canada
Investigative Site CA304
Barrie, Ontario, Canada
Investigative Site CA308
Hamilton, Ontario, Canada
Investigative Site CA303
London, Ontario, Canada
Investigative Site CA207
Mississauga, Ontario, Canada
Investigative Site CA302
Peterborough, Ontario, Canada
Investigative Site CA208
Richmond Hill, Ontario, Canada
Investigative Site CA307
Montreal, Quebec, Canada
Investigative Site CA206
Saint-Jérôme, Quebec, Canada
Investigative Site CA203
St. John's, Canada
Investigative Site CZ301
Ostrava - Poruba, Czechia
Investigative Site CZ300
Prague, Czechia
Investigative Site DK200
Århus N, Denmark
Investigative Site DK201
Roskilde, Denmark
Investigative Site FR305
Bordeaux, France
Investigative Site FR303
Brest, France
Investigative Site FR205
Dijon, France
Investigative Site FR307
Le Mans, France