Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast
Sponsor: Boehringer Ingelheim
Summary
This study is open to people with idiopathic pulmonary fibrosis (IPF) or progressive pulmonary fibrosis (PPF). They can only take part if they have completed treatment in a previous study with a medicine called nerandomilast or BI 1015550. The goal of this study is to find out how well people with pulmonary fibrosis tolerate long- term treatment with nerandomilast. The study also tests whether nerandomilast improves lung function and prolongs the time until symptoms get worse, participants need to go to the hospital, or die. Every participant takes nerandomilast as tablets for up to 1 year and 10 months. The participants may also continue their regular treatment for pulmonary fibrosis during the study. Participants visit their doctors regularly. During these visits, the doctors collect information on any health problems of the participants. Participants also regularly do lung function tests.
Official title: An Open-label Extension Trial of the Long-term Safety and Efficacy of BI 1015550 Taken Orally in Patients With Idiopathic Pulmonary Fibrosis (IPF) and Progressive Pulmonary Fibrosis (PPF) (FIBRONEER™-ON)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1666
Start Date
2024-09-26
Completion Date
2027-05-07
Last Updated
2026-10-28
Healthy Volunteers
No
Interventions
Nerandomilast
Nerandomilast
Locations (375)
University of Alabama at Birmingham
Birmingham, Alabama, United States
University of Arizona
Tucson, Arizona, United States
University of Southern California
Los Angeles, California, United States
Cedars-Sinai Medical Center
Los Angeles, California, United States
University of California Los Angeles
Los Angeles, California, United States
University of California Davis
Sacramento, California, United States
National Jewish Health
Denver, Colorado, United States
Yale University School of Medicine
New Haven, Connecticut, United States
Christiana Hospital
Newark, Delaware, United States
Georgetown University
Washington D.C., District of Columbia, United States
St. Francis Medical Institute
Clearwater, Florida, United States
University of Florida
Gainesville, Florida, United States
Clinical Research Specialists LLC - Kissimmee
Kissimmee, Florida, United States
Advanced Pulmonary Research Institute
Loxahatchee Groves, Florida, United States
Piedmont Physicians Pulmonary & Sleep Medicine of Buckhead
Atlanta, Georgia, United States
The Emory Clinic
Atlanta, Georgia, United States
Northshore University Health System
Evanston, Illinois, United States
University of Kansas Medical Center
Kansas City, Kansas, United States
Tulane Medical Center
New Orleans, Louisiana, United States
Johns Hopkins Hospital
Baltimore, Maryland, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
Brigham and Women's Hospital
Boston, Massachusetts, United States
St. Elizabeth's Medical Center
Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
University of Michigan
Ann Arbor, Michigan, United States
Corewell Health William Beaumont University Hospital
Royal Oak, Michigan, United States
University of Minnesota
Minneapolis, Minnesota, United States
Mayo Clinic, Rochester
Rochester, Minnesota, United States
The Lung Research Center, LLC
Chesterfield, Missouri, United States
Creighton University
Omaha, Nebraska, United States
University of Nebraska Medical Center
Omaha, Nebraska, United States
Renown Regional Medical Center
Reno, Nevada, United States
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States
Northern Westchester Hospital
Mount Kisco, New York, United States
New York Presbyterian Hospital -Columbia University
New York, New York, United States
NewYork-Presbyterian/Weill Cornell Medical Center
New York, New York, United States
Duke University Medical Center
Durham, North Carolina, United States
Southeastern Research Center-Winston Salem-69289
Winston-Salem, North Carolina, United States
University of Cincinnati
Cincinnati, Ohio, United States
Cleveland Clinic
Cleveland, Ohio, United States
The Ohio State University Wexner Medical Center
Columbus, Ohio, United States
The Oregon Clinic
Portland, Oregon, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
Temple University
Philadelphia, Pennsylvania, United States
Allegheny General Hospital
Pittsburgh, Pennsylvania, United States
Infinity Medical Research, Inc.
East Providence, Rhode Island, United States
Lowcountry Lung and Critical Care
Charleston, South Carolina, United States
Clinical Trials Center of Middle Tennessee, LLC
Franklin, Tennessee, United States
Vanderbilt University Medical Center
Nashville, Tennessee, United States
Baylor University Medical Center
Dallas, Texas, United States
UT Health San Antonio
San Antonio, Texas, United States
Renovatio Clinical-The Woodlands-69551
The Woodlands, Texas, United States
Intermountain Medical Center-Murray-69497
Murray, Utah, United States
University of Utah Health Sciences Center
Salt Lake City, Utah, United States
University of Vermont
Burlington, Vermont, United States
Inova Fairfax Hospital
Falls Church, Virginia, United States
Virginia Mason Medical Center
Seattle, Washington, United States
University of Wisconsin
Madison, Wisconsin, United States
Centro de Investigaciones Metabolicas (CINME)
C.a.b.a, Argentina
Fundacion NIBA Neurologia Infantil Buenos Aires
CABA, Argentina
Hospital Italiano de Buenos Aires
CABA, Argentina
Consultorios Medicos del Buen Ayre
Capital Federal, Argentina
CEMER-Centro Medico De Enfermedades Respiratorias
Florida, Argentina
Instituto Ave Pulmo - Fundacion Enfisema
Mar del Plata, Argentina
INSARES
Mendoza, Argentina
Centro Respiratorio de Quilmes
Quilmes, Argentina
Instituto Medico de la Fundacion Estudios Clinicos
Rosario, Argentina
Canberra Hospital
Garran, Australian Capital Territory, Australia
Royal Prince Alfred Hospital
Camperdown, New South Wales, Australia
Westmead Hospital
Westmead, New South Wales, Australia
Lung Research Queensland
Chermside, Queensland, Australia
The Prince Charles Hospital
Chermside, Queensland, Australia
Royal Adelaide Hospital
Adelaide, South Australia, Australia
Austin Hospital
Heidelberg, Victoria, Australia
The Alfred Hospital
Melbourne, Victoria, Australia
Fiona Stanley Hospital
Murdoch, Western Australia, Australia
Trialswest
Spearwood, Western Australia, Australia
Macquarie University
Macquarie Park, Australia
Krems University Hospital
Krems, Austria
LKH Salzburg University Hospital
Salzburg, Austria
Medical University of Vienna
Vienna, Austria
Standort Penzing der Klinik Ottakring
Vienna, Austria
Clinic Floridsdorf
Vienna, Austria
Klinikum Wels - Grieskirchen GmbH
Wels, Austria
Ziekenhuis Netwerk Antwerpen (ZNA) - Campus Middelheim
Antwerp, Belgium
Hopital Erasme
Brussels, Belgium
Cliniques Universitaires Saint-Luc
Brussels, Belgium
Universitair Ziekenhuis Gent
Ghent, Belgium
UZ Leuven
Leuven, Belgium
Centre Hospitalier Universitaire de Liège
Liège, Belgium
Yvoir - UNIV UCL de Mont-Godinne
Yvoir, Belgium
Serviços Medicos Respirar Sul Fluminense
Barra Mansa, Brazil
Hospital das Clinicas da Universidade Federal de Minas Gerais (HC-UFMG)
Belo Horizonte,Minas Gerais, Brazil
SAPIENS - Instituto de Estudos e Pesquisa Clinica
Curitiba, Brazil
CLARE - Clinica de Pneumologia
Goiânia, Brazil
Irmandade Santa Casa de Misericordia de Porto Alegre
Porto Alegre, Brazil
Hospital Nossa Senhora da Conceição
Porto Alegre - RS, Brazil
CEMEC - Centro Multidisciplinar de Estudos Clínicos
São Bernardo do Campo, Brazil
Hospital Alemao Oswaldo Cruz
São Paulo, Brazil
Hospital das Clinicas da Faculdade de Medicina da USP
São Paulo, Brazil