Clinical Research Directory

Inclusion Criteria: 1. aged 20-60 years old, 2. self-reported Insomnia (PSQI ≥ 7 \& 22 \> ISI ≥ 12), 3. 17.5 \< BMI \< 35 kg/m\^2, and 4. regular sleep cycle. Exclusion Criteria: 1. used antibiotic, sleep aids, tranquilizers, or antipsychotic treatment within the last month, 2. used other probiotic products within the last month, 3. taking medications known to commonly induce sleep disorders (such as corticosteroids, antihistamines, and stimulants, etc.) or currently undergoing hormone therapy, including contraceptive pills, 4. have undergone hepatobiliary gastrointestinal tract surgery 5. lactic acid bacteria allergy, 6. with cancer, cardiovascular disease, psychiatric illness, or kidney disease, 7. with uncontrolled diabetes mellitus or hypertension, 8. with sleep disorders other than insomnia, 9. allergic to lactobacillus, 10. reported tobacco, alcohol, caffeine or drug addiction, 11. traveled to different time zone in long-distance trip within the last month, 12. participated in other interventional studies within the last three months, and 13. evaluated as unsuitable participant by PI.