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GEnomic Medicine in Kidney Transplantation Study
Sponsor: Western Sydney Local Health District
Summary
Investigator led, prospective, observational cohort study to detect genomic features which can predict outcomes following kidney transplantation. 1. Determine non-HLA genomic mismatches between donor-recipient pairs which impact kidney allograft survival following transplantation 2. Derive polygenic risk scores on pre-transplant blood and/or kidney biopsy samples which predict kidney allograft dysfunction 3. Derive polygenic risk scores on post-transplant blood and/or kidney biopsy samples which predict kidney allograft dysfunction
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
1000
Start Date
2025-11-01
Completion Date
2035-01-01
Last Updated
2026-10-14
Healthy Volunteers
Not specified
Interventions
Biomarker discovery and validation - with focus on genomic biomarkers
Biomarker discovery and validation - with focus on genomic biomarkers
Locations (1)
Westmead Institute for Medical Research
Westmead, New South Wales, Australia