Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
Sponsor: Hoffmann-La Roche
Summary
The study will assess the efficacy and safety of pegozafermin administered in participants with biopsy-confirmed and clinically confirmed compensated cirrhosis due to MASH .
Official title: A Phase 3 Study to Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Compensated Cirrhosis Due to Metabolic Dysfunction-Associated Steatohepatitis (MASH) (ENLIGHTEN-Cirrhosis)
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
1800
Start Date
2024-05-24
Completion Date
2031-08-31
Last Updated
2026-10-23
Healthy Volunteers
No
Interventions
Pegozafermin
Subcutaneous injection
Placebo
Subcutaneous injection
Locations (330)
89bio Clinical Study Site
Birmingham, Alabama, United States
89bio Clinical Study Site
Homewood, Alabama, United States
89bio Clinical Study Site
Chandler, Arizona, United States
89bio Clinical Study Site
Flagstaff, Arizona, United States
89bio Clinical Study Site
Peoria, Arizona, United States
89bio Clinical Study Site
Phoenix, Arizona, United States
89bio Clinical Study Site
Sun City, Arizona, United States
89bio Clinical Study Site
Tucson, Arizona, United States
89bio Clinical Study Site
Tucson, Arizona, United States
89bio Clinical Study Site
Tucson, Arizona, United States
89bio Clinical Study Site
Little Rock, Arkansas, United States
89bio Clinical Study Site
North Little Rock, Arkansas, United States
89bio Clinical Study Site
Camarillo, California, United States
89bio Clinical Study Site
Canoga Park, California, United States
89bio Clinical Study Site
Coronado, California, United States
89bio Clinical Study Site
Fountain Valley, California, United States
89bio Clinical Study Site
Fresno, California, United States
89bio Clinical Study Site
Huntington Park, California, United States
89bio Clinical Study Site
La Jolla, California, United States
89bio Clinical Study Site
Los Angeles, California, United States
89bio Clinical Study Site
Los Angeles, California, United States
89bio Clinical Study Site
Pasadena, California, United States
89bio Clinical Study Site
Poway, California, United States
89bio Clinical Study Site
Redwood City, California, United States
89bio Clinical Study Site
Rialto, California, United States
89bio Clinical Study Site
Sacramento, California, United States
89bio Clinical Study Site
Santa Ana, California, United States
89bio Clinical Study Site
Littleton, Colorado, United States
89bio Clinical Study Site
Clermont, Florida, United States
89bio Clinical Study Site
Fort Myers, Florida, United States
89bio Clinical Study Site
Gainesville, Florida, United States
89bio Clinical Study Site
Hialeah Gardens, Florida, United States
89bio Clinical Study Site
Homestead, Florida, United States
89bio Clinical Study Site
Jacksonville, Florida, United States
89bio Clinical Study Site
Jacksonville, Florida, United States
89bio Clinical Study Site
Lady Lake, Florida, United States
89bio Clinical Study Site
Lakewood Rch, Florida, United States
89bio Clinical Study Site
Lehigh Acres, Florida, United States
89bio Clinical Study Site
Maitland, Florida, United States
89bio Clinical Study Site
Miami, Florida, United States
89bio Clinical Study Site
Miami, Florida, United States
89bio Clinical Study Site
Miami, Florida, United States
89bio Clinical Study Site
Miami, Florida, United States
89bio Clinical Study Site
New Port Richey, Florida, United States
89bio Clinical Study Site
Ocala, Florida, United States
89bio Clinical Study Site
Ocoee, Florida, United States
89bio Clinical Study Site
Orlando, Florida, United States
89bio Clinical Study Site
University Park, Florida, United States
89bio Clinical Study Site
Viera, Florida, United States
89bio Clinical Study Site
Winter Park, Florida, United States
89bio Clinical Study Site
Athens, Georgia, United States
89bio Clinical Study Site
Atlanta, Georgia, United States
89bio Clinical Study Site
Marietta, Georgia, United States
89bio Clinical Study Site
Chicago, Illinois, United States
89bio Clinical Study Site
Glenview, Illinois, United States
89bio Clinical Study Site
Hammond, Indiana, United States
89bio Clinical Study Site
New Albany, Indiana, United States
89bio Clinical Study Site
South Bend, Indiana, United States
89bio Clinical Study Site
Iowa City, Iowa, United States
89bio Clinical Study Site
Kansas City, Kansas, United States
89bio Clinical Study Site
Topeka, Kansas, United States
89bio Clinical Study Site
Louisville, Kentucky, United States
89bio Clinical Study Site
Lafayette, Louisiana, United States
89bio Clinical Study Site
Lake Charles, Louisiana, United States
89bio Clinical Study Site
West Monroe, Louisiana, United States
89bio Clinical Study Site
Baltimore, Maryland, United States
89bio Clinical Study Site
Glen Burnie, Maryland, United States
89bio Clinical Study Site
Greenbelt, Maryland, United States
89bio Clinical Study Site
Burlington, Massachusetts, United States
89bio Clinical Study Site
Framingham, Massachusetts, United States
89bio Clinical Study Site
Ann Arbor, Michigan, United States
89bio Clinical Study Site
Clinton Township, Michigan, United States
89bio Clinical Study Site
Detroit, Michigan, United States
89bio Clinical Study Site
Wyoming, Michigan, United States
89bio Clinical Study Site
Ypsilanti, Michigan, United States
89bio Clinical Study Site
Minneapolis, Minnesota, United States
89bio Clinical Study Site
Rochester, Minnesota, United States
89bio Clinical Study Site
Flowood, Mississippi, United States
89bio Clinical Study Site
Tupelo, Mississippi, United States
89bio Clinical Study Site
St Louis, Missouri, United States
89bio Clinical Study Site
St Louis, Missouri, United States
89bio Clinical Study Site
Las Vegas, Nevada, United States
89bio Clinical Study Site
Florham Park, New Jersey, United States
89bio Clinical Study Site
Somers Point, New Jersey, United States
89bio Clinical Study Site
Albuquerque, New Mexico, United States
89bio Clinical Study Site
Albany, New York, United States
89bio Clinical Study Site
New York, New York, United States
89bio Clinical Study Site
New York, New York, United States
89bio Clinical Study Site
New York, New York, United States
89bio Clinical Study Site
Asheville, North Carolina, United States
89bio Clinical Study Site
Charlotte, North Carolina, United States
89bio Clinical Study Site
Durham, North Carolina, United States
89bio Clinical Study Site
Fayetteville, North Carolina, United States
89bio Clinical Study Site
Greenville, North Carolina, United States
89bio Clinical Study Site
Winston-Salem, North Carolina, United States
89bio Clinical Study Site
Akron, Ohio, United States
89bio Clinical Study Site
Cincinnati, Ohio, United States
89bio Clinical Study Site
Cleveland, Ohio, United States
89bio Clinical Study Site
Columbus, Ohio, United States
89bio Clinical Study Site
Dayton, Ohio, United States