Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria
Sponsor: Celldex Therapeutics
Summary
The purpose of this study is to establish the efficacy, safety and tolerability of barzolvolimab in adult participants with Chronic Spontaneous Urticaria (CSU) inadequately controlled by non-sedating second generation H1-antihistamines in comparison to placebo.
Official title: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Barzolvolimab in Patients With Chronic Spontaneous Urticaria Who Remain Symptomatic Despite H1 Antihistamine Treatment (EMBARQ-CSU1)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
963
Start Date
2024-07-11
Completion Date
2027-04
Last Updated
2026-03-25
Healthy Volunteers
No
Conditions
Interventions
barzolvolimab
Subcutaneous Administration
Matching placebo
Matching placebo Subcutaneous Administration
Locations (235)
Cahaba Dermatology Skin Health Center
Birmingham, Alabama, United States
First OC Dermatology - Fountain Valley
Fountain Valley, California, United States
310 Clinical Research
Inglewood, California, United States
Dermatology Research Associates
Los Angeles, California, United States
Focus Clinical Research - Los Angeles
Los Angeles, California, United States
Cura Clinical Research
Oxnard, California, United States
Allergy and Asthma Consultants
Redwood City, California, United States
Acclaim Clinical Research
San Diego, California, United States
West Dermatology Research Center
San Diego, California, United States
Therapeutics Clinical Research
San Diego, California, United States
Orso Health, Inc.
Torrance, California, United States
Integrated Research of Inland, Inc.
Upland, California, United States
Western States Clinical Research Inc
Wheat Ridge, Colorado, United States
Encore Medical Research Boynton Beach
Boynton Beach, Florida, United States
Direct Helpers Research Center
Hialeah, Florida, United States
GSI Clinical Research
Margate, Florida, United States
International Dermatology Research Inc - Miami
Miami, Florida, United States
Miami Dade Medical Research Institute, LLC
Miami, Florida, United States
Sarasota Clinical Research
Sarasota, Florida, United States
GCP Global Clinical Professionals, LLC
St. Petersburg, Florida, United States
Paradigm Clinical Research Boise
Boise, Idaho, United States
Endeavor Health
Skokie, Illinois, United States
Dawes Fretzin Clinical Research Group-7910 N Shadeland Ave
Indianapolis, Indiana, United States
DS Research of Kentucky, LLC
Louisville, Kentucky, United States
Allergy and Asthma Specialists PSC
Owensboro, Kentucky, United States
Clinical Trials Management LLC - Southshore Office
Metairie, Louisiana, United States
Johns Hopkins Asthma and Allergy Center
Baltimore, Maryland, United States
DermAssociates, LLC
Rockville, Maryland, United States
Institute For Asthma and Allergy
Wheaton, Maryland, United States
David Fivenson MD Dermatolgy PLLC
Ann Arbor, Michigan, United States
Resp Medicine Research Institute of MI
Ypsilanti, Michigan, United States
Dermatolgy and Skin Cancer Center
Lee's Summit, Missouri, United States
MediSearch, LLC
Saint Joseph, Missouri, United States
Montana Medical Research
Missoula, Montana, United States
Excel Clinical Research - Las Vegas
Las Vegas, Nevada, United States
Allergy Partners of N.J., P.C.
Ocean City, New Jersey, United States
Finger Lakes Medical Research, PLLC
Cortland, New York, United States
Sadick Research Group
New York, New York, United States
Bexley Dermatology Research
Bexley, Ohio, United States
Apex Clinical Research
Canton, Ohio, United States
Bernstein Clinical Research Center, LLC
Cincinnati, Ohio, United States
Wright State Physicians
Fairborn, Ohio, United States
Auni Allergy
Findlay, Ohio, United States
Apex Clinical Research Center
Mayfield Heights, Ohio, United States
Toledo Institute of Clinical Research
Toledo, Ohio, United States
Allergy Asthma and Clinical Research Center
Oklahoma City, Oklahoma, United States
Portland Allergy and Asthma
Clackamas, Oregon, United States
Oregon Medical Research Center
Portland, Oregon, United States
Clinical Research Philadelphia, LLC
Philadelphia, Pennsylvania, United States
National Allergy and Asthma Research, LLC - CRN - PPDS
North Charleston, South Carolina, United States
Alina Clinical Trials
Dallas, Texas, United States
Zenos Clinical Research
Dallas, Texas, United States
Epic Clinical Research
Lewisville, Texas, United States
VAST Clinical Research - Plano
Plano, Texas, United States
STAAMP Research, LLC - CRN
San Antonio, Texas, United States
Allergy and Asthma Care of Waco
Waco, Texas, United States
University of Utah - MidValley Dermatology - PPDS
Murray, Utah, United States
Premier Clinical Research
Spokane, Washington, United States
Buenos Aires Skin
Buenos Aires, Buenos Aires, Argentina
Fundacion Cidea
Buenos Aires, Buenos Aires, Argentina
CEMLO:Centro de Especialidades Medicas Lobos
Lobos, Buenos Aires, Argentina
Hospital Italiano De Buenos Aires
Buenos Aires, Buenos Aires F.D., Argentina
Conexa Investigacion Clinica
CABA, Buenos Aires F.D., Argentina
Aprillus Asistencia e Investigacion
CABA, Buenos Aires F.D., Argentina
CARE- Centro de Alergia y Enfermedades Respiratorias
CABA, Buenos Aires F.D., Argentina
Centro Respiratorio Infantil
Rosario, Sante Fe, Argentina
Instituto de Especialidades de Salud Rosario
Rosario, Sante Fe, Argentina
Servicio de Investigacion de Patologias Alergicas
Rosario, Sante Fe, Argentina
Instituto Medico de la Fundacion Estudios Clinicos
Rosario, Sante Fe, Argentina
C.I.C.E 9 de Julio - Sanatorio 9 de Julio S.A.
San Miguel de Tucumán, Tucumán Province, Argentina
Clinica Mayo
San Miguel de Tucumán, Tucumán Province, Argentina
Centro de Investigaciones Medicas Tucuman
San Miguel de Tucumán, Tucumán Province, Argentina
Centro Médico Vitae
Buenos Aires, Argentina
Instituto de Alergia e Inmunologia del Sur
Buenos Aires, Argentina
UZ Antwerp
Edegem, Antwerpen, Belgium
UZ Leuven
Leuven, Vlaams Brabant, Belgium
UZ Brussel
Brussels, Belgium
Saint Luc
Brussels, Belgium
CHU de Liège
Brussels, Belgium
Hôpital Erasme - Erasme Medical Center - PPDS
Brussels, Belgium
UZ Gent
Ghent, Belgium
Dermatologie Maldegem
Maldegem, Belgium
AlergoAlpha Allergia e Immunologia
Barueri, Brazil
Instituto de Pesquisas Clínicas LTDA Brasilia
Brasília, Brazil
Fundação Universidade de Caxias do Sul - Instituto de Pesquisas em Saúde
Caxias do Sul, Brazil
Centro Paraibano de Pesquisas e Estudos Clínicos
João Pessoa, Brazil
Hospital Sao Lucas Da Pontificia Universidade Catolica Do Rio Grande Do Sul (PUCRS)
Porto Alegre, Brazil
Hospital Universitário Clementino Fraga Filho (UFRJ)
Rio de Janeiro, Brazil
Clinica IBIS
Salvador, Brazil
Centro de Estudos de Pneumologia da Faculdade de Medecina do ABC
Santo André, Brazil
Centro de Pesquisa SVRI Hospital e Maternidade Christóvão da Gama
Santo André, Brazil
Clínica de Alergia Martti Antila
São Paulo, Brazil
Vidamed Care Clínica E Residência
Vitória, Brazil
"Medical center MedTech Services" OOD
Haskovo, Bulgaria
Diagnostic Consultative Center Pulmed
Plovdiv, Bulgaria
Aipsimpa D-R Talyat Sali Cholak Eood
Razgrad, Bulgaria
Medical Center Iskar EOOD
Sofia, Bulgaria
MC Excelsior OOD
Sofia, Bulgaria
DCC Fokus - 5 OOD LZIBP
Sofia, Bulgaria
Medical Center Hera EOOD
Sofia, Bulgaria