Clinical Research Directory

Inclusion Criteria: * Diagnosis of Parkinson's disease * Able to provide written informed consent * Over 50 years old * Motor symptom duration over 12 months * Stable dopaminergic medication regime for at least 3 months Exclusion Criteria: * Use of probiotic supplements and probiotic-fortified foods (such as probiotic drinks and yoghurts) within past 3 months * Use of antibiotics within past 3 months * Previous gastrointestinal surgery or chronic organic bowel disorder * History of clinically significant motor fluctuations * History of postural instability or falls * Current smoker * Known or suspected allergy to probiotics * Regular use of antacids, proton pump inhibitors, laxatives or anti-diarrheal drugs * Use of hypoglycaemic or diabetes drugs * Participation in clinical trial of investigational medicinal product within past 3 months * Co-morbidities or other factors that, in the opinion of the investigator, make the patient unlikely to comply with study protocol