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A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
Sponsor: Akero Therapeutics, Inc
Summary
This is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in subjects with compensated cirrhosis due to NASH/MASH.
Official title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
2150
Start Date
2024-10-04
Completion Date
2030-03
Last Updated
2026-10-13
Healthy Volunteers
No
Conditions
Interventions
Efruxifermin
Administered by subcutaneous injection
Placebo
Administered by subcutaneous injection
Locations (345)
Akero Clinical Study Site
Birmingham, Alabama, United States
Akero Clinical Study Site
Dothan, Alabama, United States
Akero Clinical Study Site
Chandler, Arizona, United States
Akero Clinical Study Site
Flagstaff, Arizona, United States
Akero Clinical Study Site
Peoria, Arizona, United States
Akero Clinical Study Site
Scottsdale, Arizona, United States
Akero Clinical Study Site
Tucson, Arizona, United States
Akero Clinical Study Site
Tucson, Arizona, United States
Akero Clinical Study Site
Tucson, Arizona, United States
Akero Clinical Study Site
Tucson, Arizona, United States
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Conway, Arkansas, United States
Akero Clinical Study Site
Jonesboro, Arkansas, United States
Akero Clinical Study Site
Little Rock, Arkansas, United States
Akero Clinical Study Site
North Little Rock, Arkansas, United States
Akero Clinical Study Site
Coronado, California, United States
Akero Clinical Study Site
Escondido, California, United States
Akero Clinical Study Site
Folsom, California, United States
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Fountain Valley, California, United States
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Lancaster, California, United States
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Long Beach, California, United States
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Los Angeles, California, United States
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Los Angeles, California, United States
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Newport Beach, California, United States
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Orange, California, United States
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Pasadena, California, United States
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Redwood City, California, United States
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Sacramento, California, United States
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San Francisco, California, United States
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San Francisco, California, United States
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San Jose, California, United States
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Tarzana, California, United States
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Aurora, Colorado, United States
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Colorado Springs, Colorado, United States
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Englewood, Colorado, United States
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New Haven, Connecticut, United States
Akero Clinical Study Site
Washington D.C., District of Columbia, United States
Akero Clinical Study Site
Bradenton, Florida, United States
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Brandon, Florida, United States
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Cutler Bay, Florida, United States
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Daytona Beach, Florida, United States
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Doral, Florida, United States
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Fort Myers, Florida, United States
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Hialeah Gardens, Florida, United States
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Inverness, Florida, United States
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Lady Lake, Florida, United States
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Lakewood Rch, Florida, United States
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Largo, Florida, United States
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Lehigh Acres, Florida, United States
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Margate, Florida, United States
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Miami, Florida, United States
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Miami, Florida, United States
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Miami Gardens, Florida, United States
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Naples, Florida, United States
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New Port Richey, Florida, United States
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Ocala, Florida, United States
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Orlando, Florida, United States
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Orlando, Florida, United States
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Pembroke Pines, Florida, United States
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Riverview, Florida, United States
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Sarasota, Florida, United States
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Temple Terrace, Florida, United States
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Venice, Florida, United States
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Viera, Florida, United States
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Weston, Florida, United States
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Zephyrhills, Florida, United States
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Atlanta, Georgia, United States
Akero Clinical Study Site
Atlanta, Georgia, United States
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Gainesville, Georgia, United States
Akero Clinical Study Site
Marietta, Georgia, United States
Akero Clinical Study Site
Snellville, Georgia, United States
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Chicago, Illinois, United States
Akero Clinical Study Site
Hammond, Indiana, United States
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Indianapolis, Indiana, United States
Akero Clinical Study Site
South Bend, Indiana, United States
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West Des Moines, Iowa, United States
Akero Clinical Study Site
Topeka, Kansas, United States
Akero Clinical Study Site
Louisville, Kentucky, United States
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Bastrop, Louisiana, United States
Akero Clinical Study Site
Covington, Louisiana, United States
Akero Clinical Study Site
Houma, Louisiana, United States
Akero Clinical Study Site
Lafayette, Louisiana, United States
Akero Clinical Study Site
Marrero, Louisiana, United States
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Metairie, Louisiana, United States
Akero Clinical Study Site
Shreveport, Louisiana, United States
Akero Clinical Study Site
West Monroe, Louisiana, United States
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Baltimore, Maryland, United States
Akero Clinical Study Site
Bethesda, Maryland, United States
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South Dartmouth, Massachusetts, United States
Akero Clinical Study Site
Clinton Township, Michigan, United States
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Novi, Michigan, United States
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Southfield, Michigan, United States
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Rochester, Minnesota, United States
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Flowood, Mississippi, United States
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Columbia, Missouri, United States
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Kansas City, Missouri, United States
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St Louis, Missouri, United States
Akero Clinical Study Site
St Louis, Missouri, United States
Akero Clinical Study Site
Henderson, Nevada, United States
Akero Clinical Study Site
Las Vegas, Nevada, United States
Akero Clinical Study Site
Jackson, New Jersey, United States