Clinical Research Directory

Inclusion Criteria: * Be at least 40 years of age, but no more than 85 years of age at time of consent, of any sex or race; * Have chronic, moderate, osteoarthritic-related knee pain occurring with ambulation; * NRS Pain score reaches between 4/10 or greater 4+ days a week, as assessed by practitioner; * Have a Kellgren and Lawrence score of 2,3, or 4, as demonstrated by x-ray within the last 2 years; * Be able to walk unassisted for at least 10 minutes at a time; * Wear a women's shoe size of U.S. 7 to 14 or a men's shoe size of U.S. 6 to 13; * Not currently enrolled in a supervised physical therapy program for knee pain; * Have access and ability to use a smart phone. Exclusion Criteria: * Be diagnosed with acute septic or inflammatory arthritis; * Be considered a High Fall Risk (3+ falls in last year, TUG \>21 seconds, TURN180 \>4 steps) * Have unstable cardiovascular, orthopedic, or neurological conditions, uncontrolled diabetes, or any condition that would preclude exercise in moderate duration, or moderate workload trials; * Have received a corticosteroid injection for knee pain or invasive procedures within prior 3 months of the study; * Have history of avascular necrosis in the knee; * Have experienced more than 3 falls within the last year; * Have a pathological osteoporotic fracture; * Have severe symptomatic degenerative arthritis in lower limb joints other than the knees; * Have severe back pain, prior spinal fusion, or spinal deformity that would affect gait; * Have major cardiac or pulmonary conditions and any orthopedic limitation that precludes your ability to independently walk for 10 minutes or longer; * Have any major surgery to either knee within the prior 12 months; * Be currently enrolled in a supervised physical therapy program; * Be currently using any knee brace on a regular basis for knee pain, with the exception of basic knee sleeves; * Have previous partial knee joint replacement; * Have previous total knee joint replacement.