Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC
Sponsor: AstraZeneca
Summary
The purpose of ARTEMIDE-Lung03 is to evaluate the efficacy and safety of rilvegostomig compared to pembrolizumab, both in combination with platinum-based doublet chemotherapy, as a first-line treatment of patients with locally advanced or metastatic non-squamous NSCLC whose tumors express PD-L1.
Official title: A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab in Combination With Platinum-based Chemotherapy for the First-line Treatment of Patients With Locally Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer Whose Tumors Express PD-L1 (ARTEMIDE-Lung03)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1160
Start Date
2024-11-27
Completion Date
2030-11-18
Last Updated
2026-10-28
Healthy Volunteers
No
Conditions
Interventions
Rilvegostomig
Administered as one intravenously (IV) on Day 1 of each 21-day cycle
Pembrolizumab
Administered as one intravenously (IV) on Day 1 of each 21-day cycle
Carboplatin
Administered as one intravenously (IV) on Day 1 of each 21-day cycle up to 4 cycles
Cisplatin
Administered as one intravenously (IV) on Day 1 of each 21-day cycle up to 4 cycles
Pemetrexed
Administered as one intravenously (IV) on Day 1 of each 21-day cycle
Locations (301)
Research Site
Mobile, Alabama, United States
Research Site
Chandler, Arizona, United States
Research Site
Phoenix, Arizona, United States
Research Site
Anaheim, California, United States
Research Site
Beverly Hills, California, United States
Research Site
Loma Linda, California, United States
Research Site
Redlands, California, United States
Research Site
San Diego, California, United States
Research Site
San Francisco, California, United States
Research Site
Santa Rosa, California, United States
Research Site
Walnut Creek, California, United States
Research Site
Lone Tree, Colorado, United States
Research Site
Stamford, Connecticut, United States
Research Site
West Haven, Connecticut, United States
Research Site
Newark, Delaware, United States
Research Site
Bay Pines, Florida, United States
Research Site
Fort Lauderdale, Florida, United States
Research Site
Gainesville, Florida, United States
Research Site
Jacksonville, Florida, United States
Research Site
Miami, Florida, United States
Research Site
Ocala, Florida, United States
Research Site
St. Petersburg, Florida, United States
Research Site
Atlanta, Georgia, United States
Research Site
Boise, Idaho, United States
Research Site
Chicago, Illinois, United States
Research Site
Decatur, Illinois, United States
Research Site
Hinsdale, Illinois, United States
Research Site
Quincy, Illinois, United States
Research Site
Rockford, Illinois, United States
Research Site
Waterloo, Iowa, United States
Research Site
Lexington, Kentucky, United States
Research Site
Lexington, Kentucky, United States
Research Site
Louisville, Kentucky, United States
Research Site
Alexandria, Louisiana, United States
Research Site
Baton Rouge, Louisiana, United States
Research Site
Shreveport, Louisiana, United States
Research Site
Shreveport, Louisiana, United States
Research Site
South Portland, Maine, United States
Research Site
Baltimore, Maryland, United States
Research Site
Bethesda, Maryland, United States
Research Site
Grand Rapids, Michigan, United States
Research Site
Duluth, Minnesota, United States
Research Site
Rochester, Minnesota, United States
Research Site
Saint Paul, Minnesota, United States
Research Site
Bridgeton, Missouri, United States
Research Site
Columbia, Missouri, United States
Research Site
Lincoln, Nebraska, United States
Research Site
Camden, New Jersey, United States
Research Site
Buffalo, New York, United States
Research Site
Westbury, New York, United States
Research Site
Canton, Ohio, United States
Research Site
Medford, Oregon, United States
Research Site
Portland, Oregon, United States
Research Site
Salem, Oregon, United States
Research Site
Pittsburgh, Pennsylvania, United States
Research Site
York, Pennsylvania, United States
Research Site
Providence, Rhode Island, United States
Research Site
Pierre, South Dakota, United States
Research Site
Sioux Falls, South Dakota, United States
Research Site
Chattanooga, Tennessee, United States
Research Site
Nashville, Tennessee, United States
Research Site
Fort Worth, Texas, United States
Research Site
Houston, Texas, United States
Research Site
Irving, Texas, United States
Research Site
Kingwood, Texas, United States
Research Site
Lubbock, Texas, United States
Research Site
Palestine, Texas, United States
Research Site
Round Rock, Texas, United States
Research Site
Fairfax, Virginia, United States
Research Site
Norfolk, Virginia, United States
Research Site
Roanoke, Virginia, United States
Research Site
Seattle, Washington, United States
Research Site
Seattle, Washington, United States
Research Site
Silverdale, Washington, United States
Research Site
Spokane, Washington, United States
Research Site
Tacoma, Washington, United States
Research Site
Wenatchee, Washington, United States
Research Site
La Crosse, Wisconsin, United States
Research Site
Buenos Aires, Argentina
Research Site
CABA, Argentina
Research Site
La Plata, Argentina
Research Site
Pilar, Argentina
Research Site
Rosario, Argentina
Research Site
Darlinghurst, Australia
Research Site
Hyde Park, Australia
Research Site
Southport, Australia
Research Site
Wollongong, Australia
Research Site
Brussels, Belgium
Research Site
Charleroi, Belgium
Research Site
Kortrijk, Belgium
Research Site
Ottignies, Belgium
Research Site
Sint-Niklaas, Belgium
Research Site
Ijuí, Brazil
Research Site
Londrina, Brazil
Research Site
Passo Fundo, Brazil
Research Site
Porto Alegre, Brazil
Research Site
Salvador, Brazil
Research Site
São Paulo, Brazil
Research Site
São Paulo, Brazil
Research Site
São Paulo, Brazil