Clinical Research Directory
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A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3)
Sponsor: Eli Lilly and Company
Summary
The purpose of this study is to measure the difference in time to developing or worsening memory, thinking, or functional problems due to Alzheimer's disease occurring in participants receiving study drug compared to placebo. Participation could last up to 255 weeks including screening, a double-blind treatment period, and a double-blind observation period. In addition, eligible participants who receive placebo during the double-blind treatment period may choose to extend their study participation to receive open-label remternetug in an extension period.
Official title: A Study of Remternetug Versus Placebo in Early Alzheimer's Disease Participants at Risk for Cognitive and Functional Decline
Key Details
Gender
All
Age Range
55 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
1400
Start Date
2024-10-24
Completion Date
2030-10
Last Updated
2026-10-07
Healthy Volunteers
No
Conditions
Interventions
Remternetug
Administered SC
Placebo
Administered SC
Locations (262)
Parkway Medical Center
Birmingham, Alabama, United States
MD First Research - Chandler
Chandler, Arizona, United States
Care Access - 801 South Power Road, Mesa
Mesa, Arizona, United States
Banner Alzheimer's Institute
Phoenix, Arizona, United States
Banner Alzheimer's Institute Tucson
Tucson, Arizona, United States
Neuro-Pain Medical Center
Fresno, California, United States
Care Access - Huntington Beach
Huntington Beach, California, United States
Inglewood Clinical
Inglewood, California, United States
Irvine Clinical Research
Irvine, California, United States
Healthy Brain Clinic
Long Beach, California, United States
Riverside Clinical
Riverside, California, United States
Clinical Trials Research
Sacramento, California, United States
Artemis Institute for Clinical Research
San Diego, California, United States
Sharp Neurocognitive Research Center
San Diego, California, United States
Ray Dolby Brain Health Center
San Francisco, California, United States
The Neuron Clinic - San Marcos
San Marcos, California, United States
Syrentis Clinical Research
Santa Ana, California, United States
Providence Medical Foundation
Santa Rosa, California, United States
California Neuroscience Research, LLC
Sherman Oaks, California, United States
Care Access - Aurora
Aurora, Colorado, United States
Mountain Neurological Research Center
Basalt, Colorado, United States
Alpine Clinical Research Center
Boulder, Colorado, United States
CenExel Rocky Mountain Clinical Research
Englewood, Colorado, United States
Invicro
New Haven, Connecticut, United States
Ki Health Partners, LLc, dba New England Institute for Clinical Research
Stamford, Connecticut, United States
JEM Research Institute
Atlantis, Florida, United States
VIN - Aventura
Aventura, Florida, United States
Bradenton Research Center, Inc.
Bradenton, Florida, United States
K2 Medical Research WINTER GARDEN
Clermont, Florida, United States
TecTum Research
Davie, Florida, United States
Brain Matters Research
Delray Beach, Florida, United States
Neuropsychiatric Research Center of Southwest Florida
Fort Myers, Florida, United States
Indago Research & Health Center, Inc
Hialeah, Florida, United States
K2 MEDICAL Research THE VILLAGES
Lady Lake, Florida, United States
ClinCloud
Maitland, Florida, United States
K2 Medical Research ORLANDO
Maitland, Florida, United States
ClinCloud
Melbourne, Florida, United States
Merritt Island Medical Research, LLC
Merritt Island, Florida, United States
VIN-Andrew Lerman
Miami, Florida, United States
New Age Medical Research Corporation
Miami, Florida, United States
Adult Medicine of Lake County, Inc.
Mt. Dora, Florida, United States
Aqualane Clinical Research
Naples, Florida, United States
Suncoast Clinical Research, Inc.
New Port Richey, Florida, United States
Renstar Medical Research
Ocala, Florida, United States
Charter Research - Winter Park
Orlando, Florida, United States
AdventHealth Orlando
Orlando, Florida, United States
Emerald Coast Neurology - Airport Boulevard
Pensacola, Florida, United States
Progressive Medical Research
Port Orange, Florida, United States
Alzheimer's Research and Treatment Center
Stuart, Florida, United States
Axiom Brain Health LLC
Tampa, Florida, United States
Stedman Clinical Trials
Tampa, Florida, United States
Care Access - Tampa
Tampa, Florida, United States
Charter Research - Lady Lake
The Villages, Florida, United States
Alzheimer's Research and Treatment Center
Wellington, Florida, United States
Palm Beach Neurology
West Palm Beach, Florida, United States
Conquest Research
Winter Park, Florida, United States
Columbus Memory Center, LLC
Columbus, Georgia, United States
Care Access - Decatur
Decatur, Georgia, United States
Center for Advanced Research & Education
Gainesville, Georgia, United States
North Georgia Clinical Research
Woodstock, Georgia, United States
Northwest Clinical Trials
Boise, Idaho, United States
Care Access - Arlington Heights
Arlington Heights, Illinois, United States
Re:Cognition Health - Chicago
Chicago, Illinois, United States
Great Lakes Clinical Trials - Andersonville
Chicago, Illinois, United States
Alexian Brothers Medical Center
Elk Grove Village, Illinois, United States
Care Access - South Indianapolis
Indianapolis, Indiana, United States
Josephson Wallack Munshower Neurology, PC
Indianapolis, Indiana, United States
Cedar Valley Medical Specialists
Waterloo, Iowa, United States
Cotton O'Neil Clinical Research Center
Topeka, Kansas, United States
Care Access - Lake Charles (Bayou Pines)
Lake Charles, Louisiana, United States
Tandem Clinical Research
Marrero, Louisiana, United States
Acadia Hospital
Bangor, Maine, United States
Care Access - Baltimore
Baltimore, Maryland, United States
Adams Clinical Boston
Boston, Massachusetts, United States
Boston Clinical Trials
Boston, Massachusetts, United States
Boston Center for Memory
Newton, Massachusetts, United States
Care Access - Quincy
Quincy, Massachusetts, United States
MedVadis Research Corporation
Waltham, Massachusetts, United States
Adams Clinical Watertown
Watertown, Massachusetts, United States
Revival Research Institute, LLC
Dearborn, Michigan, United States
QUEST Research Institute
Farmington Hills, Michigan, United States
HealthPartners Neuroscience Center
Saint Paul, Minnesota, United States
Private Practice - Dr. Ronald Louis Schwartz
Hattiesburg, Mississippi, United States
Citizens Memorial Hospital District
Bolivar, Missouri, United States
Clinical Research Professionals
Chesterfield, Missouri, United States
University Of Nebraska Medical Center
Omaha, Nebraska, United States
Vector Clinical Trials
Las Vegas, Nevada, United States
Care Access - Hoboken
Hoboken, New Jersey, United States
The Cognitive and Research Center of New Jersey - Ridgewood
Ridgewood, New Jersey, United States
The Cognitive and Research Center of New Jersey
Springfield, New Jersey, United States
Advanced Memory Research Institute of New Jersey
Toms River, New Jersey, United States
IMA Clinical Research
Albuquerque, New Mexico, United States
Care Access - Charlotte
Charlotte, North Carolina, United States
Medication Management
Greensboro, North Carolina, United States
Monroe Biomedical Research
Monroe, North Carolina, United States
Care Access - Lima
Lima, Ohio, United States
North Star Medical Research
Middleburg Heights, Ohio, United States
Summit Headlands
Portland, Oregon, United States
Clinical Research of Philadelphia
Philadelphia, Pennsylvania, United States
Keystone Clinical Studies
Plymouth Meeting, Pennsylvania, United States