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Research on the Use of Probiotics in the Prevention and Treatment of Inflammatory Bowel Disease
Sponsor: Wecare Probiotics Co., Ltd.
Summary
This study evaluates oral Lactobacillus reuteri as an adjunct therapy for 2 months. Endoscopic assessments will be performed at baseline and after 2 months of intervention to evaluate intestinal inflammation. Intestinal fluid samples will be collected during endoscopy for 16S rRNA gene sequencing to assess changes in the gut microbiota. Peripheral blood inflammatory markers and fecal calprotectin levels will also be measured to evaluate changes in intestinal inflammation.
Official title: Application Research of Lactobacillus Reuteri in the Treatment of Inflammatory Bowel
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
41
Start Date
2025-01-25
Completion Date
2026-06-30
Last Updated
2026-10-28
Healthy Volunteers
No
Conditions
Interventions
Probiotic
The experimental phase of the study lasts 8 weeks and each patient will be visited 4 times.
Locations (1)
Gastroenterology Department of Jiangsu Province （Suqian）Hospital
Suqian, Jiangsu, China