Clinical Research Directory

Inclusion Criteria: * • Patient age should be between 18-50 years * Should be able to give written informed consent * Should have systemic status (ASA 1) * Should have permanent molar or premolar (lower and upper) root development * Should be asymptomatic, deep (D3) or extremely deep (D4) caries * Should give vital response in cold test and electric pulp test * Should have teeth where the pulp is exposed with caries * Should not have pain during palpation and percussion * Should not have periodontal disease * Should have restorable teeth * Should have teeth without pulp necrosis, sinus tract or swelling/abscess * Should have bleeding time less than 10 minutes * Should be able to include a maximum of two teeth in a patient in the study (should be in different quadrants and there should be at least 2 weeks between treatment periods) Exclusion Criteria: * Teeth with incomplete root development * Severely affected teeth that do not respond to pulp sensitivity tests * Teeth with signs and symptoms of irreversible pulpitis * Teeth without signs of bleeding after communicating with the pulp chamber * Teeth with pulp chamber open to the oral environment * Teeth with periodontal pockets greater than 4 mm deep * Teeth with suspected cracks or crown fractures that may be responsible for pulp pathology * Teeth with uncontrolled bleeding * Medically at-risk patients will be excluded from the study.