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SUSPENDED
NCT06902753
NA

Adaptation and Normalization of a Verbal Episodic Memory Test in French Sign Language

Sponsor: Poitiers University Hospital

View on ClinicalTrials.gov

Summary

To date, neuropsychological assessment of deaf signing persons is complicated by a lack of resources, especially the absence of tools available in French Sign Language (LSF). This is due to perceptual and cultural differences, and in particular the linguistic differences between French and LSF. This lack of resources significantly hinders access to care for deaf patients, as neuropsychological assessment is often a key clinical criterion in the diagnosis of certain neurological pathologies (Alzheimer's disease in particular) and enables coherent care plans to be drawn up, for example in the aftermath of strokes or traumatic brain injuries. In particular, episodic memory (which refers to the ability to memorise information anchored in a specific context) is a cognitive domain that is sensitive to pathologies such as Alzheimer's disease, but it is not currently possible to assess it with deaf signing patients. The aim of this study is to create a memory assessment test adapted to a deaf population that expresses in LSF and to normalize this test on this same population. The aim is to provide a diagnosis assessment tool, which currently does not exist in France, to improve access to care for deaf people. This project could then be extended to the creation of tests for other cognitive domains (executive functions, attention, social cognition, etc.) and to prospects for cognitive remediation. The 16-item Free and Cued Recall test (RL-RI 16) is the best choice because it is easy to use and accurate enough to assess each stage of episodic memory. These qualities make it a decisive tool in certain differential diagnosis.

Official title: Adaptation and Normalization of a Verbal Episodic Memory Test (16-item Free and Cued Recall / RL-RI 16) in French Sign Language

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

120

Start Date

2025-05-05

Completion Date

2028-08

Last Updated

2026-10-27

Healthy Volunteers

Yes

Interventions

OTHER

Questionnaire and Physical Exam

Phase 1: Single-visit with assessment of cognitive performance (MMS-LS) and fluency tasks (verbal flexibility)

OTHER

Questionnaire and Physical Exam

Phase 2: * Inclusion visit (M0) with assessment of cognitive performance (MMS-LS), administration of the RL-RI-LSF test, Rey-Osterrieth complex figure and WAIS-IV subtests (matrix reasoning, symbol search, coding). * Follow-up visit (M9) with assessment of cognitive performance (MMS-LS), administration of the RL-RI-LSF test, Rey-Osterrieth complex figure and WAIS-IV subtests (matrix reasoning, symbol search, coding).

Locations (1)

Poitiers University Hospital

Poitiers, France