Clinical Research Directory
Browse clinical research sites, groups, and studies.
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Sponsor: Amgen
Summary
The primary objective of this trial is to demonstrate that maridebart cafraglutide is superior to placebo when given as an adjunct to standard of care with respect to reducing cardiovascular (CV) morbidity and mortality.
Official title: A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Key Details
Gender
All
Age Range
45 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
12800
Start Date
2025-07-25
Completion Date
2030-09-29
Last Updated
2026-10-29
Healthy Volunteers
No
Interventions
Maridebart Cafraglutide
Maridebart cafraglutide will be administered SC.
Placebo
Placebo will be administered SC.
Locations (783)
Alliance For Multispecialty Research - Daphne
Daphne, Alabama, United States
Eastern Shore Research Institute
Fairhope, Alabama, United States
Huntsville Clinical Research, LLC
Huntsville, Alabama, United States
Mobile Heart Specialists PC
Mobile, Alabama, United States
Syed Research Consultants LLC
Sheffield, Alabama, United States
Synexus Clinical Research US, Inc.
Phoenix, Arizona, United States
Medical Advancement Centers of Arizona
Phoenix, Arizona, United States
Valley Clinical Trials, LLC dba Flourish Research
Covina, California, United States
Velocity Clinical Research- Huntington Park
Huntington Park, California, United States
Velocity Clinical Research- Los Angeles
La Mesa, California, United States
Orange County Research Center
Lake Forest, California, United States
Biopharma Informatic - The Cardiovascular Center
Redding, California, United States
Acclaim Clinical Research
San Diego, California, United States
Encompass Clinical Research
Spring Valley, California, United States
Diablo Clinical Research
Walnut Creek, California, United States
Focus Clinical Research
West Hills, California, United States
Family Practice Associates
Wilmington, Delaware, United States
Excel Medical Clinical Trials
Boca Raton, Florida, United States
Velocity Clinical Research - New Smyrna Beach
Edgewater, Florida, United States
Alliance for Multispecialty Research - Fort Myers
Fort Myers, Florida, United States
Elite Cardiac Research Center LLC
Hialeah, Florida, United States
Elite Clinical Research
Hialeah, Florida, United States
Zenith Clinical Research
Hollywood, Florida, United States
Encore Medical Research LLC
Hollywood, Florida, United States
East Coast Institute for Research, LLC
Jacksonville, Florida, United States
Clinical Research of Central Florida
Lakeland, Florida, United States
South Florida Clinical Research
Margate, Florida, United States
Finlay Medical Research
Miami, Florida, United States
Suncoast Research Group LLC
Miami, Florida, United States
New Horizon Research Center
Miami, Florida, United States
Panax Clinical Research
Miami Lakes, Florida, United States
San Marcus Research Clinic Inc
Miami Lakes, Florida, United States
Indago Research and Health Center
Miami Lakes, Florida, United States
West Orange Endocrinology
Ocoee, Florida, United States
Cardiology Partners Clinical Research Institute
Palm Beach Gardens, Florida, United States
Peace River Cardiovascular Center
Port Charlotte, Florida, United States
Progressive Medical Research
Port Orange, Florida, United States
Saint Johns Center for Clinical Research
Saint Augustine, Florida, United States
Intercoastal Medical Group
Sarasota, Florida, United States
Winter Haven Hospital
Winter Haven, Florida, United States
East Coast Institute for Research LLC at Canton Georgia
Canton, Georgia, United States
The Jones Center Clinical Research
Macon, Georgia, United States
Velocity Clinical Research - Savannah
Savannah, Georgia, United States
Velocity Clinical Research - Boise
Meridian, Idaho, United States
Endeavor Health-Northwest Community Healthcare
Arlington Heights, Illinois, United States
Eagle Clinical Research
Chicago, Illinois, United States
University of Chicago
Chicago, Illinois, United States
Alliance For Multispecialty Research - Oak Brook
Oak Brook, Illinois, United States
Prarie Education and Research
Springfield, Illinois, United States
Cardiovascular Research of Northwest Indiana LLC
Munster, Indiana, United States
Velocity Clinical Research - Valparaiso
Valparaiso, Indiana, United States
McFarland Clinic PC
Ames, Iowa, United States
Midwest Cardiovascular Research Foundation
Davenport, Iowa, United States
Cotton-ONeil Diabetes and Endocrinology Center
Topeka, Kansas, United States
Monroe Biomedical Research
Louisville, Kentucky, United States
Cardiovascular Associates Research, LLC
Covington, Louisiana, United States
Tandem Clinical Research - Marrero
Marrero, Louisiana, United States
Ascension Saint Agnes Heart Care
Baltimore, Maryland, United States
MD Medical Research
Oxon Hill, Maryland, United States
Velocity Clinical Research - Rockville
Rockville, Maryland, United States
Brigham and Womens Hospital
Boston, Massachusetts, United States
Btc of New Bedford
New Bedford, Massachusetts, United States
Fairview Health Services M Health Fairview St Johns Hospital
Maplewood, Minnesota, United States
Minneapolis Heart Institute Foundation
Minneapolis, Minnesota, United States
Jackson Heart Clinic
Jackson, Mississippi, United States
Cardiology Associates of North Mississippi
Tupelo, Mississippi, United States
StudyMetrix Research
City of Saint Peters, Missouri, United States
Alliance for Multispecialty Research - Kansas City
Kansas City, Missouri, United States
Kansas City Veterans Affairs Medical Center
Kansas City, Missouri, United States
Saint Louis Heart and Vascular PC
St Louis, Missouri, United States
Bryan Heart
Lincoln, Nebraska, United States
University of Nebraska Medical Center
Omaha, Nebraska, United States
Primary Clinical Research
Papillion, Nebraska, United States
Excel Clinical Research
Las Vegas, Nevada, United States
Vector Clinical Trials
Las Vegas, Nevada, United States
CardioMetabolic Collaborative Clinic
Somerset, New Jersey, United States
Velocity Clinical Research - Binghamton
Binghamton, New York, United States
Hudson Valley Cardiovascular Practice PC
Poughkeepsie, New York, United States
Rochester Clinical Research
Rochester, New York, United States
Saratoga Clinical Research, LLC
Saratoga Springs, New York, United States
Southgate Medical Group
West Seneca, New York, United States
Novant Health Heart and Vascular Institute
Charlotte, North Carolina, United States
Velocity Clinical Research - Durham
Durham, North Carolina, United States
Moses H Cone Memorial Hospital
Greensboro, North Carolina, United States
Monroe Biomedical Research
Monroe, North Carolina, United States
West Clinical Research
Morehead City, North Carolina, United States
Burke Primary Care Family Practice
Morganton, North Carolina, United States
Accellacare of Raleigh
Raleigh, North Carolina, United States
Accellacare of Piedmont Healthcare
Statesville, North Carolina, United States
Brookview Hills Research Associates Llc
Winston-Salem, North Carolina, United States
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States
Velocity Clinical Research - Cleveland
Beachwood, Ohio, United States
Aultman Hospital, Cardiovascular Consultants, Inc
Canton, Ohio, United States
Velocity Clinical Research - Auburn
Cincinnati, Ohio, United States
Endocrinology Associates Inc
Columbus, Ohio, United States
Nexgen Research
Lima, Ohio, United States
Alliance for Multispecialty Research - Norman
Norman, Oklahoma, United States
Heritage Valley Multispecialty Group Inc
Beaver, Pennsylvania, United States
Capital Area Research LLC
Camp Hill, Pennsylvania, United States
Abington Medical Specialists
Horsham, Pennsylvania, United States