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A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Sponsor: AstraZeneca
Summary
This Phase IIb dose-ranging study will evaluate the efficacy and safety of 2 different doses of AZD6793 compared with placebo tablets in participants with moderate to very severe chronic obstructive pulmonary disease.
Official title: A Multicentre, Parallel-group, Phase IIb, Randomised, Double-blind, Placebo-controlled, 3-Arm, 24-Week Study to Evaluate the Efficacy and Safety of AZD6793 Tablets in Adult Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (PRESTO)
Key Details
Gender
All
Age Range
40 Years - Any
Study Type
INTERVENTIONAL
Enrollment
987
Start Date
2025-06-27
Completion Date
2027-08-31
Last Updated
2026-10-23
Healthy Volunteers
No
Interventions
AZD6793
Oral dosage
Placebo
Oral dosage
Locations (367)
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Birmingham, Alabama, United States
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Glendale, Arizona, United States
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Phoenix, Arizona, United States
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Phoenix, Arizona, United States
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Phoenix, Arizona, United States
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Canoga Park, California, United States
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La Mesa, California, United States
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Los Angeles, California, United States
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Newport Beach, California, United States
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Norco, California, United States
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Tustin, California, United States
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Lakewood, Colorado, United States
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Brandon, Florida, United States
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Cape Coral, Florida, United States
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Clearwater, Florida, United States
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Clearwater, Florida, United States
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Jacksonville, Florida, United States
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Lake City, Florida, United States
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Miami, Florida, United States
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Miami, Florida, United States
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Miami, Florida, United States
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Miami, Florida, United States
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Miami, Florida, United States
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Miami Lakes, Florida, United States
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Naples, Florida, United States
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Ocala, Florida, United States
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Ormond Beach, Florida, United States
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Plantation, Florida, United States
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Sarasota, Florida, United States
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Tamarac, Florida, United States
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Tampa, Florida, United States
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Tampa, Florida, United States
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Winter Park, Florida, United States
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Suwanee, Georgia, United States
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West Des Moines, Iowa, United States
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Lexington, Kentucky, United States
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Zachary, Louisiana, United States
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Baltimore, Maryland, United States
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Baltimore, Maryland, United States
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Burlington, Massachusetts, United States
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Farmington Hills, Michigan, United States
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Garden City, Michigan, United States
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Grand Rapids, Michigan, United States
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Chesterfield, Missouri, United States
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Hannibal, Missouri, United States
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St Louis, Missouri, United States
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St Louis, Missouri, United States
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Missoula, Montana, United States
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Mount Kisco, New York, United States
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New Bern, North Carolina, United States
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Cleveland, Ohio, United States
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Marion, Ohio, United States
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Oklahoma City, Oklahoma, United States
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Tulsa, Oklahoma, United States
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Medford, Oregon, United States
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Portland, Oregon, United States
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Camp Hill, Pennsylvania, United States
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DuBois, Pennsylvania, United States
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Philadelphia, Pennsylvania, United States
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Philadelphia, Pennsylvania, United States
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Pittsburgh, Pennsylvania, United States
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Scottdale, Pennsylvania, United States
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Smithfield, Pennsylvania, United States
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Lancaster, South Carolina, United States
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Spartanburg, South Carolina, United States
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Rapid City, South Dakota, United States
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Chattanooga, Tennessee, United States
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Franklin, Tennessee, United States
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Johnson City, Tennessee, United States
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Boerne, Texas, United States
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Dallas, Texas, United States
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Denison, Texas, United States
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El Paso, Texas, United States
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Houston, Texas, United States
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Houston, Texas, United States
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Houston, Texas, United States
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Kingwood, Texas, United States
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Lewisville, Texas, United States
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Mansfield, Texas, United States
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McKinney, Texas, United States
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Pearland, Texas, United States
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Colchester, Vermont, United States
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Norfolk, Virginia, United States
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Williamsburg, Virginia, United States
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Morgantown, West Virginia, United States
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Madison, Wisconsin, United States
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Alberdi, Argentina
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CABA, Argentina
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Ciudad Autónoma de Bs As, Argentina
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Ciudad de Buenos Aires, Argentina
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Ciudad de Buenos Aires, Argentina
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Mar del Plata, Argentina
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Mar del Plata, Argentina
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Mendoza, Argentina
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Ranelagh, Argentina
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Rosario, Argentina
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San Miguel de Tucumán, Argentina
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Cairns, Australia
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Nedlands, Australia
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Norwood, Australia