Clinical Research Directory
Browse clinical research sites, groups, and studies.
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
Sponsor: Sanofi
Summary
This is a parallel, Phase 2b/Phase 3, 3-arm study to investigate the efficacy, safety, and tolerability of subcutaneous (SC) treatment with lunsekimig compared with placebo in adult participants (aged 40 to 80 years, inclusive) with inadequately controlled Chronic obstructive pulmonary disease (COPD) characterized by an eosinophilic phenotype. Participation to the study consists of 3 periods: * Screening period of up to 4 weeks * Randomized intervention period of approximately 48 weeks * Follow-up period: Approximately 8 weeks The study duration will be up to 60 weeks.
Official title: A Phase 2b/Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study, to Investigate the Efficacy and Safety of Lunsekimig in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Key Details
Gender
All
Age Range
40 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
942
Start Date
2025-09-17
Completion Date
2030-01-22
Last Updated
2026-10-23
Healthy Volunteers
No
Conditions
Interventions
Lunsekimig
Pharmaceutical form: solution for injection in prefilled syringe. Route of administration: Subcutaneous injection
Placebo
Pharmaceutical form: solution for injection. Route of administration: Subcutaneous injection
Locations (314)
University of Alabama at Birmingham- Site Number : 8400003
Birmingham, Alabama, United States
Pulmonary Associates - Mobile- Site Number : 8400151
Mobile, Alabama, United States
Tucson Clinical Research Institute- Site Number : 8400006
Tucson, Arizona, United States
Ark Clinical Research- Site Number : 8400113
Long Beach, California, United States
Inglewood Clinical- Site Number : 8400074
Los Angeles, California, United States
Alliance Clinical - West Hills- Site Number : 8400067
Los Angeles, California, United States
California Medical Research Associates - Northridge- Site Number : 8400089
Northridge, California, United States
Acclaim Clinical Research- Site Number : 8400068
San Diego, California, United States
Alpine Clinical Research Center - Boulder - 47th Street- Site Number : 8400005
Boulder, Colorado, United States
Critical Care Pulmonary & Sleep Associates- Site Number : 8400081
Lakewood, Colorado, United States
Howard University Hospital- Site Number : 8400080
Washington D.C., District of Columbia, United States
Meris Clinical Research- Site Number : 8400153
Brandon, Florida, United States
Hillcrest Medical Research- Site Number : 8400082
DeLand, Florida, United States
Finlay Medical Research - Greenacres- Site Number : 8400107
Greenacres City, Florida, United States
Direct Helpers Research Center- Site Number : 8400057
Hialeah, Florida, United States
University of Florida - Jacksonville- Site Number : 8400126
Jacksonville, Florida, United States
Salud Clinical Services- Site Number : 8400109
Lehigh Acres, Florida, United States
Pulmonary Specialists of the Palm Beaches- Site Number : 8400017
Loxahatchee Groves, Florida, United States
Elite Clinical Research - Miami- Site Number : 8400167
Miami, Florida, United States
DL Research Solutions- Site Number : 8400140
Miami, Florida, United States
Phoenix Medical Research - Miami - 24th Street- Site Number : 8400027
Miami, Florida, United States
Professional Research Center- Site Number : 8400046
Miami, Florida, United States
Research Institute of South Florida- Site Number : 8400028
Miami, Florida, United States
Innovations Biotech- Site Number : 8400019
Miami, Florida, United States
Heuer M.D. Research- Site Number : 8400018
Orlando, Florida, United States
Florida Institute for Clinical Research- Site Number : 8400001
Orlando, Florida, United States
Avanza Medical Research Center- Site Number : 8400015
Pensacola, Florida, United States
Hull and Hull Medical Specialists- Site Number : 8400002
Plantation, Florida, United States
Windom Allergy, Asthma and Sinus Specialists- Site Number : 8400041
Sarasota, Florida, United States
Stat Care Pulmonary and Sleep- Site Number : 8400138
St. Petersburg, Florida, United States
Better Life Clinical Research- Site Number : 8400152
Tampa, Florida, United States
Vicis Clinical Research- Site Number : 8400158
Tampa, Florida, United States
Appalachian Clinical Research- Site Number : 8400060
Adairsville, Georgia, United States
Christie Clinic in Champaign on University- Site Number : 8400023
Champaign, Illinois, United States
Sneeze Wheeze & Itch Associates- Site Number : 8400020
Normal, Illinois, United States
Peoria Pulmonary Associates Ltd- Site Number : 8400095
Peoria, Illinois, United States
Asha Clinical Research - Munster- Site Number : 8400115
Hammond, Indiana, United States
Ochsner LSU Health Shreveport - Academic Medical Center- Site Number : 8400083
Shreveport, Louisiana, United States
Care Access - Shreveport - Youree Drive- Site Number : 8400007
Shreveport, Louisiana, United States
Johns Hopkins Bayview Medical Center- Site Number : 8400076
Baltimore, Maryland, United States
Lucida Clinical Trials- Site Number : 8400101
New Bedford, Massachusetts, United States
Vitalis Clinical Research Center- Site Number : 8400040
Allen Park, Michigan, United States
Bolt Clinical Research- Site Number : 8400086
Brighton, Michigan, United States
Henry Ford Hospital- Site Number : 8400058
Detroit, Michigan, United States
Pulmonary Research Institute of Southeast Michigan - Farmington Hills- Site Number : 8400161
Farmington Hills, Michigan, United States
Hannibal Regional Healthcare System- Site Number : 8400035
Hannibal, Missouri, United States
Washington University- Site Number : 8400144
St Louis, Missouri, United States
Excel Clinical Research - Las Vegas- Site Number : 8400070
Las Vegas, Nevada, United States
AB Clinical Trials- Site Number : 8400075
Las Vegas, Nevada, United States
Bioluminux Clinical Research - Hamilton, New Jersey- Site Number : 8400037
Hamilton, New Jersey, United States
Rutgers Institute For Infectious & Inflammatory Diseases (I3d)- Site Number : 8400093
Newark, New Jersey, United States
Trinity Medical, WNY- Site Number : 8400157
Buffalo, New York, United States
Mid Hudson Medical Research - New Windsor- Site Number : 8400004
New Windsor, New York, United States
East Carolina University- Site Number : 8400102
Greenville, North Carolina, United States
Piedmont Healthcare - Family Medicine- Site Number : 8400022
Statesville, North Carolina, United States
All-Trials Clinical Research- Site Number : 8400008
Winston-Salem, North Carolina, United States
Asthma & Allergy Center - Toledo- Site Number : 8400110
Toledo, Ohio, United States
Layrek Clinical Research- Site Number : 8400066
Tulsa, Oklahoma, United States
The Oregon Clinic - Portland - Northwest 22nd Avenue- Site Number : 8400065
Portland, Oregon, United States
Suburban Research Associates - Media- Site Number : 8400143
Media, Pennsylvania, United States
MedTrial- Site Number : 8400010
Columbia, South Carolina, United States
Chattanooga Research and Medicine- Site Number : 8400026
Chattanooga, Tennessee, United States
Premier Research Center, Llc- Site Number : 8400146
Hendersonville, Tennessee, United States
Solace Clinical Research- Site Number : 8400087
Austin, Texas, United States
IntraCare- Site Number : 8400034
Dallas, Texas, United States
Premier Pulmonary Critical Care and Sleep- Site Number : 8400111
Denison, Texas, United States
El Paso Pulmonary Association- Site Number : 8400033
El Paso, Texas, United States
Axsendo Clinical Research - Houston- Site Number : 8400054
Houston, Texas, United States
Se Houston- Site Number : 8400120
Houston, Texas, United States
Aavon Clinical Trials, Llc- Site Number : 8400166
Houston, Texas, United States
Synergy Group US - Missouri City- Site Number : 8400119
Missouri City, Texas, United States
Synergy Group US - Missouri City- Site Number : 8400133
Missouri City, Texas, United States
Elligo Health Care, Hillcroft Medical Clinic Association- Site Number : 8400053
Sugar Land, Texas, United States
Medrasa Clinical Research - Wylie- Site Number : 8400124
Wylie, Texas, United States
Rheumatology & Pulmonary Clinic- Site Number : 8400012
Beckley, West Virginia, United States
Investigational Site Number : 0320011
Berazategui, Buenos Aires, Argentina
Investigational Site Number : 0320004
Buenos Aires, Argentina
Investigational Site Number : 0320002
Buenos Aires, Argentina
Investigational Site Number : 0320005
Buenos Aires, Argentina
Investigational Site Number : 0320003
Buenos Aires, Argentina
Investigational Site Number : 0320006
Buenos Aires, Argentina
Investigational Site Number : 0320001
Buenos Aires, Argentina
Investigational Site Number : 0320012
Buenos Aires, Argentina
Investigational Site Number : 0320009
Córdoba, Argentina
Investigational Site Number : 0320007
Mendoza, Argentina
Investigational Site Number : 0320008
Mendoza, Argentina
Investigational Site Number : 0320010
Santa Fe, Argentina
Investigational Site Number : 0360007
Coffs Harbour, New South Wales, Australia
Investigational Site Number : 0360008
Tiwi, Northern Territory, Australia
Investigational Site Number : 0360006
South Brisbane, Queensland, Australia
Investigational Site Number : 0360004
Townsville, Queensland, Australia
Investigational Site Number : 0360002
Traralgon, Victoria, Australia
Investigational Site Number : 0360001
Osborne Park, Western Australia, Australia
Investigational Site Number : 5540004
Dunedin, Australia
Universidade Federal de Goias- Site Number : 0760002
Goiânia, Goiás, Brazil
Santa Casa de Misericordia de Belo Horizonte- Site Number : 0760004
Belo Horizonte, Minas Gerais, Brazil
WM Pesquisas Clínicas em Doenças Respiratórias- Site Number : 0760003
Porto Alegre, Rio Grande do Sul, Brazil
CEMEC - Centro Multidisciplinar de Estudos Clínicos - São Bernardo do Campo- Site Number : 0760001
São Bernardo do Campo, São Paulo, Brazil
IBCC - Núcleo de Pesquisa e Ensino- Site Number : 0760005
São Paulo, Brazil
Investigational Site Number : 1240051
Kelowna, British Columbia, Canada