Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)
Sponsor: AstraZeneca
Summary
The purpose of this study is to measure the efficacy and safety of rilvegostomig with gemcitabine plus cisplatin vs. durvalumab with gemcitabine plus cisplatin as first line treatment for patients with advanced BTC.
Official title: Phase III, Randomized, Open-label, Global, Multicenter Study of Rilvegostomig or Durvalumab in Combination With Chemotherapy as a First-line Treatment for Patients With Advanced Biliary Tract Cancer (ARTEMIDE-Biliary02)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1100
Start Date
2025-12-04
Completion Date
2029-07-31
Last Updated
2026-09-28
Healthy Volunteers
No
Conditions
Interventions
Rilvegostomig
Rilvegostomig IV (intravenous) Q3W
Durvalumab
Durvalumab 1500mg IV (intravenous) Q3W for up to 8 cycles (21days). Then Q4W.
Gemcitabine/Cisplatin
Gemcitabine/Cisplatin IV (Intravenous) 1000 mg/m2 plus cisplatin 25 mg/m2 on Day 1 and Day 8 of each 21-day cycle
Locations (183)
Research Site
Birmingham, Alabama, United States
Research Site
Phoenix, Arizona, United States
Research Site
Tucson, Arizona, United States
Research Site
Duarte, California, United States
Research Site
Los Angeles, California, United States
Research Site
Orange, California, United States
Research Site
Palo Alto, California, United States
Research Site
Aurora, Colorado, United States
Research Site
Hartford, Connecticut, United States
Research Site
New Haven, Connecticut, United States
Research Site
Washington D.C., District of Columbia, United States
Research Site
Washington D.C., District of Columbia, United States
Research Site
Gainesville, Florida, United States
Research Site
Jacksonville, Florida, United States
Research Site
Miami, Florida, United States
Research Site
Marietta, Georgia, United States
Research Site
Chicago, Illinois, United States
Research Site
Chicago, Illinois, United States
Research Site
Indianapolis, Indiana, United States
Research Site
Louisville, Kentucky, United States
Research Site
Louisville, Kentucky, United States
Research Site
Baltimore, Maryland, United States
Research Site
Ann Arbor, Michigan, United States
Research Site
Detroit, Michigan, United States
Research Site
Rochester, Minnesota, United States
Research Site
Omaha, Nebraska, United States
Research Site
Santa Fe, New Mexico, United States
Research Site
Mineola, New York, United States
Research Site
New York, New York, United States
Research Site
New York, New York, United States
Research Site
New York, New York, United States
Research Site
Oklahoma City, Oklahoma, United States
Research Site
Portland, Oregon, United States
Research Site
Lancaster, Pennsylvania, United States
Research Site
Philadelphia, Pennsylvania, United States
Research Site
Pittsburgh, Pennsylvania, United States
Research Site
Providence, Rhode Island, United States
Research Site
Pierre, South Dakota, United States
Research Site
Sioux Falls, South Dakota, United States
Research Site
Nashville, Tennessee, United States
Research Site
Houston, Texas, United States
Research Site
Seattle, Washington, United States
Research Site
Clayton, Australia
Research Site
Darlinghurst, Australia
Research Site
Gosford, Australia
Research Site
Murdoch, Australia
Research Site
South Brisbane, Australia
Research Site
Anderlecht, Belgium
Research Site
Edegem, Belgium
Research Site
Leuven, Belgium
Research Site
Liège, Belgium
Research Site
Roeselare, Belgium
Research Site
Barretos, Brazil
Research Site
Natal, Brazil
Research Site
Porto Alegre, Brazil
Research Site
Ribeirão Preto, Brazil
Research Site
São Paulo, Brazil
Research Site
Vitória, Brazil
Research Site
Calgary, Alberta, Canada
Research Site
Vancouver, British Columbia, Canada
Research Site
Halifax, Nova Scotia, Canada
Research Site
Barrie, Ontario, Canada
Research Site
Toronto, Ontario, Canada
Research Site
Toronto, Ontario, Canada
Research Site
Montreal, Quebec, Canada
Research Site
Québec, Quebec, Canada
Research Site
Beijing, China
Research Site
Beijing, China
Research Site
Changchun, China
Research Site
Changde, China
Research Site
Changsha, China
Research Site
Changsha, China
Research Site
Chengdu, China
Research Site
Fuzhou, China
Research Site
Guangzhou, China
Research Site
Hangzhou, China
Research Site
Hefei, China
Research Site
Kunming, China
Research Site
Lishui, China
Research Site
Luoyang, China
Research Site
Nanchang, China
Research Site
Nanning, China
Research Site
Shandong, China
Research Site
Shanghai, China
Research Site
Shenyang, China
Research Site
Weifang, China
Research Site
Wuhan, China
Research Site
Xi'an, China
Research Site
Clichy, France
Research Site
Grenoble, France
Research Site
Marseille, France
Research Site
Vandœuvre-lès-Nancy, France
Research Site
Aachen, Germany
Research Site
Berlin, Germany
Research Site
Berlin, Germany
Research Site
Bonn, Germany
Research Site
Düsseldorf, Germany
Research Site
Essen, Germany
Research Site
Frankfurt, Germany
Research Site
Freiburg im Breisgau, Germany