Clinical Research Directory

Key Inclusion Criteria: 1. Adult male and female patients with FOP, including patients who have completed the double-blind treatment period of the OPTIMA study (R2477-FOP-2175 \[NCT05394116\]). 2. If the patient has progression of disease with Cumulative Analogue Joint Involvement Scale (CAJIS) \>19 at the time of EAP enrollment, the case will require discussion and evaluation between the treating physician and EAP Medical Director to determine final eligibility Key Exclusion Criteria: 1\. Participants who participated in OPTIMA and are considered by the treating physician as inappropriate for this program for any reason NOTE: Other protocol defined inclusion / exclusion criteria apply