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A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
Sponsor: Bristol-Myers Squibb
Summary
A study to evaluate Pumitamig versus Durvalumab following concurrent chemoradiation therapy in participants with unresectable stage III Non-small Cell Lung Cancer (NSCLC)
Official title: ROSETTA Lung-201: A Randomized, Multicenter, Open-label Phase 3 Study of Pumitamig Monotherapy Compared to Durvalumab in Participants With Unresectable Stage III NSCLC Without Progression After Platinum-based Concurrent Chemoradiation Therapy.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
850
Start Date
2026-03-16
Completion Date
2034-01-13
Last Updated
2026-09-30
Healthy Volunteers
No
Conditions
Interventions
Pumitamig
Specified dose on specified days
Durvalumab
Specified dose on specified days
Locations (260)
Southern Cancer Center Pc
Daphne, Alabama, United States
Intermountain Health Cancer Center Lutheran Hospital
Golden, Colorado, United States
Medical Oncology Hematology Consultants, PA
Newark, Delaware, United States
Local Institution - 0711
Ocala, Florida, United States
Local Institution - 0935
Plantation, Florida, United States
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital
Marietta, Georgia, United States
University of Chicago Medical Center
Chicago, Illinois, United States
Endeavor Health
Evanston, Illinois, United States
Illinois Cancer Care
Peoria, Illinois, United States
Fort Wayne Medical Oncology and Hematology
Fort Wayne, Indiana, United States
University of Kentucky Chandler Medical Center
Lexington, Kentucky, United States
Local Institution - 0603
Boston, Massachusetts, United States
Karmanos Cancer Institute
Detroit, Michigan, United States
Minnesota Oncology Hematology
Maple Grove, Minnesota, United States
Allina Health Cancer Institute - Abbott Northwestern Hospital
Minneapolis, Minnesota, United States
Missouri Cancer Associates
Columbia, Missouri, United States
Memorial Sloan Kettering Cancer Center
New York, New York, United States
Local Institution - 0339
Westbury, New York, United States
Optum Medical Care, PC
Westbury, New York, United States
Novant Health Pharmacy Oncology Specialists
Winston-Salem, North Carolina, United States
Akron General Medical Center
Akron, Ohio, United States
The Christ Hospital
Cincinnati, Ohio, United States
University Hospitals Cleveland Medical Center
Cleveland, Ohio, United States
Cleveland Clinic
Cleveland, Ohio, United States
Cleveland Clinic - Hillcrest Hospital
Mayfield Heights, Ohio, United States
Oncology Associates Of Oregon, Pc
Eugene, Oregon, United States
Northwest Cancer Specialists, P.C.
Happy Valley, Oregon, United States
SCRI Oncology Partners
Nashville, Tennessee, United States
Tennessee Oncology
Nashville, Tennessee, United States
Texas Oncology - Amarillo Cancer Center
Amarillo, Texas, United States
Texas Oncology-Austin Central
Austin, Texas, United States
Texas Oncology
Denton, Texas, United States
The Center For Cancer And Blood Disorders
Fort Worth, Texas, United States
The University of Texas-MD Anderson Cancer Center
Houston, Texas, United States
Texas Oncology - San Antonio Medical Center
San Antonio, Texas, United States
Texas Oncology - Northeast Texas
Tyler, Texas, United States
Blue Ridge Cancer Care
Christiansburg, Virginia, United States
Virginia Oncology Associates
Norfolk, Virginia, United States
Instituto Argentino De Diagnostico Y Tratamiento IADT
Buenas Aires, Buenos Aires, Argentina
Investigaciones Oncologicas C Colon SA
Mar del Plata, Buenos Aires, Argentina
Hospital Privado Universitario de Córdoba
Córdoba, Córdoba Province, Argentina
Sanatorio Parque Rosario
Rosario, Santa Fe Province, Argentina
Instituto Medico Especializado Alexander Fleming
Buenos Aires, Argentina
Clinica Adventista Belgrano
Buenos Aires, Argentina
Hospital Italiano de Buenos Aires
Buenos Aires, Argentina
Instituto de Investigaciones Clínicas Córdoba S.A.
Córdoba, Argentina
Gosford Hospital
Gosford, New South Wales, Australia
Nepean Hospital
Penrith, New South Wales, Australia
Westmead Hospital
Westmead, New South Wales, Australia
Lyell McEwin Hospital
Elizabeth Vale, South Australia, Australia
Grampians Health
Ballarat Central, Victoria, Australia
Northern Hospital
Epping, Victoria, Australia
Joondalup Health Campus
Joondalup, Western Australia, Australia
Universitätsklinik Innsbruck
Innsbruck, Austria
Ordensklinikum Linz GmbH Elisabethinen
Linz, Austria
Medizinische Universitaet Wien/AKH
Vienna, Austria
Local Institution - 0122
Anderlecht, Bruxelles-Capitale, Région de, Belgium
Grand Hôpital de Charleroi
Charleroi, Hainaut, Belgium
Ziekenhuis Oost-Limburg, Campus St.-Jan
Genk, Limburg, Belgium
UZ Gent
Ghent, Oost-Vlaanderen, Belgium
VITAZ
Sint-Niklaas, Oost-Vlaanderen, Belgium
UZ Leuven
Leuven, Vlaams-Brabant, Belgium
Algemeen Ziekenhuis klina
Brasschaat, Belgium
Vencer Centro de Pesquisa LTDA
Teresina, Piauí, Brazil
Liga Norte Riograndense Contra o Câncer
Natal, Rio Grande do Norte, Brazil
Hospital de Clinicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil
Fundação Pio XII - Hospital de Câncer de Barretos
Barretos, São Paulo, Brazil
Fundação Faculdade Regional de Medicina de São José do Rio Preto
São José do Rio Preto, São Paulo, Brazil
Icesp - Instituto Do Câncer Do Estado de São Paulo
São Paulo, Brazil
Multiprofile Hospital for Active Treatment - Haskovo AD
Haskovo, Bulgaria
Complex Oncology Center - Ruse EOOD
Rousse, Bulgaria
"Sveta Ekaterina" Hospital
Sofia, Bulgaria
University Multiprofile Hospital for Active Treatment Tsaritsa Yoanna - ISUL EAD
Sofia, Bulgaria
Diagnostic and Consultative Center Convex
Sofia, Bulgaria
The Ottawa Hospital - General Campus
Ottawa, Ontario, Canada
St. Marys Hospital Center
Montreal, Quebec, Canada
IUCPQ
Québec, Canada
Bradford Hill Norte
Antofagasta, AN, Chile
Centro de Oncología de Precisión
Las Condes, Arica y Parinacota Region, Chile
FALP
Santiago, Santiago Metropolitan, Chile
Bradfordhill
Santiago, Santiago Metropolitan, Chile
Oncocentro APYS - Centro de Atencion Medica Oncologica Integral
Viña del Mar, Valparaiso, Chile
Beijing Cancer hospital
Beijing, Beijing Municipality, China
Chongqing University Cancer Hospital
Chongqing, Chongqing Municipality, China
Fujian Cancer Hospital
Fuzhou, Fujian, China
Cancer Hospital of Shantou University Medical College
Shantou, Guangdong, China
Peking University Shenzhen Hospital
Shenzhen, Guangdong, China
Local Institution - 0249
Zhengzhou, Henan, China
Jingzhou First People's Hospital
Jingzhou, Hubei, China
The Central Hospital of Wuhan
Wuhan, Hubei, China
Local Institution - 0813
Wuhan, Hubei, China
Local Institution - 0489
Changsha, Hunan, China
The First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China
The Second Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China
Local Institution - 0242
Shenyang, Liaoning, China
The Second Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China
Local Institution - 0564
Xi'an, Shaanxi, China
Qilu Hospital of Shandong University
Jinan, Shandong, China
Shandong Cancer Hospital
Jinan, Shandong, China
Local Institution - 0248
Shanghai, Shanghai Municipality, China