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Antibiotic Resistance of Helicobacter Pylori in Nanjing: A Cross-Sectional Study
Sponsor: Nanjing First Hospital, Nanjing Medical University
Summary
This study aims to provide an updated analysis of the resistance patterns of H. pylori in the Nanjing region, with a focus on characterizing the current status of phenotypic and genotypic resistance to these six antimicrobial agents. The findings are expected to offer a scientific basis for the rapid diagnosis and personalized treatment of H. pylori infection.
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
7227
Start Date
2026-03-01
Completion Date
2026-03-25
Last Updated
2026-04-09
Healthy Volunteers
No
Conditions
Interventions
Antimicrobial susceptibility testing
This study employed a retrospective, single-center, cross-sectional epidemiological design. Medical records of outpatients who underwent H. pylori culture and genetic testing at the gastroenterology clinic between 2018 and 2025 were retrospectively reviewed. The study aimed to characterize the resistance patterns of H. pylori in the Nanjing region, with a focus on elucidating the current status of phenotypic and genotypic resistance to amoxicillin, clarithromycin, metronidazole, levofloxacin, tetracycline, and furazolidone. The findings are intended to assist clinicians in the rapid diagnosis and individualized treatment of H. pylori infection.
Locations (1)
Nanjing First Hospital
Nanjing, Jiangsu, China