Clinical Research Directory

Preoperative Sleep Quality and Postoperative Outcomes in Breast Surgery

Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Summary

\* Brief Summary: This prospective, single-center observational study examined the association between preoperative sleep quality and postoperative outcomes in women undergoing elective breast cancer surgery. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), with scores ≤5 indicating good sleep quality and scores \>5 indicating poor sleep quality. The primary outcome was the systemic immune-inflammation index (SII), calculated from routine blood counts obtained 24 hours after surgery. Postoperative SII was compared between sleep-quality groups, accounting for preoperative SII and relevant clinical and surgical characteristics. Secondary outcomes included change in SII from baseline, pain intensity during the first 45 minutes in the post-anesthesia care unit (PACU), opioid consumption, rescue analgesic requirement, and length of hospital stay. Pain was assessed using a 10-cm visual analogue scale on PACU arrival and at 15, 30, and 45 minutes. Opioid consumption included morphine and tramadol administered during the final 20 minutes of surgery and the first 45 minutes in the PACU, expressed as intravenous morphine equivalents. No treatment was assigned by the study protocol. Anesthetic and analgesic management followed routine clinical practice.

Official title: Association of Preoperative Sleep Quality With 24-Hour Systemic Immune-Inflammation Index, Early PACU Pain, and Analgesic Use After Breast Cancer Surgery

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