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ENROLLING BY INVITATION
NCT07561749

SER-ABS-AUD: Neuropsychosocial-Spiritual Correlates of Serene Abstinence in Adults With AUD

Sponsor: Grigore T. Popa University of Medicine and Pharmacy

View on ClinicalTrials.gov

Summary

SER-ABS-AUD is a single-centre, non-interventional, mixed retrospective-prospective longitudinal cohort study of 70 adults aged 18-70 years with documented alcohol use disorder, at least 12 consecutive months of continuous alcohol abstinence before enrolment, and an archived pre-enrolment MCMI-IV profile. After written informed consent at the current T2 enrolment visit, archived T1 MCMI-IV data and eligible clinical information are extracted, and the MCMI-IV plus a supplementary recovery-outcome battery are administered prospectively at T2. The primary outcome is within-person change in prespecified MCMI-IV scales between archived T1 and current T2. The secondary exploratory Serene Abstinence Index combines change in MCMI-IV Persistent Depression with current T2 natural reward response, spiritual well-being, and quality of life. T2-only measures are interpreted as current outcomes or concurrent exploratory correlates, not longitudinal change. No experimental intervention or post-enrolment 12-month follow-up is included.

Official title: Neuropsychosocial-Spiritual Correlates of Serene Abstinence in Adults With Alcohol Use Disorder Receiving Community-Based Recovery Care in Romania: A Longitudinal Observational Study Protocol (SER-ABS-AUD)

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

OBSERVATIONAL

Enrollment

70

Start Date

2026-04-20

Completion Date

2027-04-20

Last Updated

2026-10-06

Healthy Volunteers

Yes

Locations (1)

Association of Recovering Alcoholics Don Orione

Iași, Iaşi, Romania