Clinical Research Directory

Inclusion Criteria: 1. Adults ≥19 years of age 2. Patients with a diagnosis of prostate adenocarcinoma for whom SBRT to the prostate +/- proximal seminal vesicles is being offered 3. Prostate gland volume less than 100 cc prior to initiation of ADT as reported at time of biopsy or by separate measure with ultrasound or other imaging modalities, including MRI or CT scan 4. PI-RADS 4 or 5 lesion seen on pretreatment MRI 5. IPSS/AUA (Appendix D, E) symptom score less than 16 Exclusion Criteria: 1. Prior treatment for prostate cancer 2. Prior solid cancer diagnosis in the last 5 years 3. Any history of anal or rectal cancer 4. Any history of invasive carcinoma of the bladder 5. History of prior circumferential resection of the rectum (such as LAR or APR) 6. History of inflammatory bowel syndromes not adequately controlled on current medication regimen 7. Urinary or fecal incontinence or chronic diarrhea requiring more than 1 pad per day