Clinical Research Directory

Multidimensional Dysfunction in Patients With Chronic Critical Illness in China

Sponsor: Hongying Jiang, MD

Summary

Over the past two decades, rapid advances in critical care medicine have markedly reduced short-term mortality among critically ill patients. As a result, a growing number of patients survive the acute phase of critical illness but do not recover quickly. Instead, they develop chronic critical illness (CCI), which is characterized by prolonged dependence on intensive care, including prolonged mechanical ventilation, persistent organ dysfunction, recurrent infections, and extended intensive care unit (ICU) stay. Patients with CCI have a heavy symptom burden and consume substantial healthcare resources, and many survivors experience persistent physical, cognitive, and psychological impairments after hospital discharge. Although CCI has gained increasing attention in recent years, existing studies still have multiple limitations. The number of patients with CCI in China continues to rise, and critical care delivery models vary widely across regions and healthcare institutions. There is therefore an urgent need for a large-scale multicenter observational study to systematically characterize the epidemiological features, multidimensional functional impairment profiles, and long-term functional outcomes of Chinese patients with CCI. The findings will provide an evidence-based foundation for developing a scientific post-ICU continuum of care for this population.

Official title: Multidimensional Dysfunction in Patients With Chronic Critical Illness in China: A Multi-center Real-world Study

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