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6-Weeks of Blood Flow Restriction Training on Immune Cell Function and Bioenergetics
Sponsor: University of British Columbia
Summary
To conduct a randomized control trial to determine the impact of 6-weeks of blood flow restriction training on immune cell function and bioenergetics in adults living with type 2 diabetes.
Official title: Impact of 6-Weeks of Blood Flow Restriction Training on Immune Cell Function and Bioenergetics in Adults withT2D
Key Details
Gender
All
Age Range
19 Years - 64 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-02-11
Completion Date
2027-12-31
Last Updated
2026-11-02
Healthy Volunteers
No
Conditions
Interventions
Exercise with BFR
Participants will complete treadmill walking on 3 days per week for 6 weeks. During the first week participants will walk continuously for 21 minutes during each training session which will be increased to 32 minutes per training session for weeks 2-6. The treadmill speed and grade will be set to elicit 40-50% heart rate reserve. The BFR cuffs will be inflated based on each participants individualized limb occlusion pressure (LOP). The cuffs will remain inflated for the entire session but will deflate for 1 min every 10 min based on safety recommendations. The percentage of LOP will progressively increase over the course of the intervention. Weeks 1 and 2 will be completed at 60% LOP, after which pressure will increase by 5% each subsequent week, corresponding to 65%, 70%, 75%, and 80% LOP during weeks 3, 4, 5, and 6, respectively.
Exercise
Participants will complete treadmill walking on 3 days per week for 6 weeks. During the first week participants will walk continuously for 21 minutes during each training session which will be increased to 32 minutes per training session for weeks 2-6. The treadmill speed and grade will be set to elicit 40-50% heart rate reserve.
Locations (1)
University of British Columbia Okanagan
Kelowna, British Columbia, Canada