Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Study of DS-3939a in Participants With Solid Tumors
Sponsor: Daiichi Sankyo
Summary
The primary purpose of the study is to evaluate the safety, tolerability, and efficacy of DS-3939a in combination with other anticancer agents or as a monotherapy in participants with solid tumors.
Official title: A Phase 1b/2, Multicenter, 2-part, Open-label Trial to Evaluate DS-3939a in Participants With Solid Tumors
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
400
Start Date
2026-10-13
Completion Date
2032-01-29
Last Updated
2026-10-28
Healthy Volunteers
No
Conditions
Interventions
DS-3939a
DS-3939a will be administered as an IV infusion.
Pembrolizumab
Pembrolizumab will be administered as an IV infusion.
Carboplatin
Carboplatin will be administered as an IV infusion.
Pemetrexed
Pemetrexed will be administered as an IV infusion.
DS-1103a
DS-1103a will be administered as an IV infusion.
Locations (76)
Highlands Oncology Group (Hog) - Fayetteville
Fayetteville, Arkansas, United States
UCLA Health
Los Angeles, California, United States
Moffitt Cancer Center - Magnolia Campus
Tampa, Florida, United States
Oregon Health & Science University
Portland, Oregon, United States
Lifespan Cancer Institute - Rhode Island Hospital
Providence, Rhode Island, United States
The University of Texas Md Anderson Cancer Center
Houston, Texas, United States
Inova Schar Cancer Institute
Fairfax, Virginia, United States
Instituto Alexander Fleming
Buenos Aires, Argentina
Instituto Oncologico de Cordoba (Ionc) - Fundacion Richardet Longo
Córdoba, Argentina
Sanatorio Parque
Rosario, Argentina
Cer San Juan - Centro Polivalente de Asistencia E Investigacion Clinica
San Juan, Argentina
Clinica Viedma S.A.
Viedma, Argentina
Medizinische Universitat Innsbruck
Innsbruck, Austria
Karl Landsteiner Institut Fur Lungenforschung Und Pneumologische Onkologie
Vienna, Austria
Universite Libre de Bruxelles (Ulb) - Institut Jules
Brussels, Belgium
Jessa Ziekenhuis - Hartcentrum Hasselt
Sint-Truiden, Belgium
Fundacao Pio Xii-Hospital de Cancer de Barretos
Barretos, Brazil
Liga Norte Riograndense Contra O Cancer - Pesquisa Clinica
Natal, Brazil
Irmandade Da Santa Casa de Misericordia de Porto Alegre
Porto Alegre, Brazil
Hospital Sao Lucas Da Pucrs
Porto Alegre, Brazil
Obras Sociais Irma Dulce - Centro de Pesquisa Oncologica E Clinica (Cpoc)
Salvador, Brazil
Hospital Israelita Albert Einstein
São Paulo, Brazil
Beijing Chest Hospital, Capital Medical University
Beijing, China
Jilin Cancer Hospital
Changchun, China
Hunan Cancer Hospital
Changsha, China
The First Affiliated Hospital, Sun Yat-Sen University
Guangzhou, China
The First Affiliated Hospital, Zhejiang University School of Medicine (Zhejiang Provincial First Hos
Hangzhou, China
Zhejiang Cancer Hospital
Hangzhou, China
Harbin Medical University Cancer Hospital
Harbin, China
Tianjin Medical University Cancer Institute and Hospital
Hexi District, Tianjin, China
Jiamusi Cancer Hospital
Jiamusi, China
Shandong University - Shandong Cancer Hospital
Jinan, China
Lin Yi Cancer Hospital
Linyi, China
Shanghai East Hospital
Shanghai, China
Taizhou Hospital of Zhejiang Province
Taizhou, China
Hubei Cancer Hospital
Wuhan, China
Henan Provincial Cancer Hospital
Zhengzhou, China
Aphm - Hopital Nord
Marseille, France
Centre Hospitalier Universitaire de Montpellier (Chu Montpellier) - Hopital Lapeyronie
Montpellier, France
Hospitalier Paris Saint-Joseph
Paris, France
Centre Hospitalier Universitaire (Chu) de Rennes - Hopital de Pontchaillou
Rennes, France
Institut de Cancerologie de L'Ouest (Ico) - Saint-Herblain
Saint-Herblain, France
Hopital Foch
Suresnes, France
Unicancer-Institut de Cancerologie de Lorraine (Icl)
Vandœuvre-lès-Nancy, France
Institut Gustave Roussy
Villejuif, France
Istituto Europeo Di Oncologia
Milan, Italy
Azienda Ospedaliero - Universitaria San Luigi Gonzaga
Orbassano, Italy
Universita Degli Studi Di Pavia-Fondazione Irccs Policlinico San Matteo
Pavia, Italy
Azienda Ospedaliera Di Perugia - Ospedale Santa Maria Della Misericordia
Perugia, Italy
Servizio Sanitario Regionale Emilia-Romagna - Azienda Unita Sanitaria Locale Della Romagna - Ospedal
Ravenna, Italy
Istituti Fisioterapici Ospitalieri (Ifo) - Istituto Nazionale Tumori Regina Elena (Ire)
Rome, Italy
Fondazione Policlinico Universitario Agostino
Rome, Italy
Kansai Medical University Hospital
Hirakata, Japan
National Cancer Center Hospital East
Kashiwa-shi, Japan
National Hospital Organization (Nho) Shikoku Cancer Center
Matsuyama, Japan
Sendai Kousei Hospital
Sendai, Japan
National Hospital Organization Hokkaido Cancer Center
Shiroishi-ku, Sapporo-shi, Japan
Hospital Del Mar
Barcelona, Spain
Hospital Universitario Arnau de Vilanova (Lleida)
Lleida, Spain
Hospital General Universitario Gregorio Maranon
Madrid, Spain
Hospital Clinico San Carlos
Madrid, Spain
Hospital Universitario Virgen de La Victoria
Málaga, Spain
Hospital Clinico Universitario de Santiago
Santiago de Compostela, Spain
Hospital Universitario Virgen Macarena
Seville, Spain
Hospital Universitario Virgen Del Rocio (Huvr)
Seville, Spain
Taichung Veterans General Hospital
Taichung, Taiwan
National Cheng Kung University Hospital Nckuh
Tainan, Taiwan
National Taiwan University Hospital
Taipei, Taiwan
Taipei Veterans General Hospital
Taipei, Taiwan
Ankara Bilkent Sehir Hastanesi (Ankara City Hospital)
Ankara, Tunisia
Memorial Ankara Hospital
Ankara, Turkey (Türkiye)
Liv Hospital Ankara
Ankara, Turkey (Türkiye)
T.C. Saglik Bakanligi Ankara Ataturk Egitim Ve Arastirma Hastanesi (Ankara Ataturk Training and Rese
Ankara, Turkey (Türkiye)
Ege Universitesi Tip Fakultesi Hastanesi
Bornova, Turkey (Türkiye)
Istanbul Medeniyet University Goztepe Prof. Dr. Suleyman Yalcin City Hospital
Istanbul, Turkey (Türkiye)
Adana City Training & Research Hospital
Yüreğir, Turkey (Türkiye)