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A Clinical Trial of MK-1406 in Healthy Participants (MK-1406-008)
Sponsor: Merck Sharp & Dohme LLC
Summary
The purpose of this trial is to compare what happens to MK-1406 in the body of healthy participants when it is given as 2-injections and 3-injections. Researchers also want to learn about the safety of MK-1406 and if people tolerate it.
Official title: A Randomized, Open Label, Parallel Group Phase 1 Study to Compare Safety, Tolerability and Pharmacokinetics of Subcutaneously Administered MK-1406 as Three Injections Compared With Two Injections in Healthy Adult Participants
Key Details
Gender
All
Age Range
18 Years - 64 Years
Study Type
INTERVENTIONAL
Enrollment
400
Start Date
2026-09-10
Completion Date
2027-02-05
Last Updated
2026-10-27
Healthy Volunteers
Yes
Conditions
Interventions
MK-1406
Subcutaneous administration
Locations (7)
Research Centers of America ( Hollywood ) ( Site 0008)
Hollywood, Florida, United States
QPS-MRA, LLC ( Site 0007)
South Miami, Florida, United States
Parexel Baltimore EPCU ( Site 0010)
Baltimore, Maryland, United States
Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0002)
Springfield, Missouri, United States
Hassman Research Institute Marlton Site ( Site 0001)
Marlton, New Jersey, United States
Velocity Clinical Research, Cleveland ( Site 0005)
Cleveland, Ohio, United States
ICON Early Phase Services ( Site 0004)
San Antonio, Texas, United States