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RECRUITING
NCT07783737

China Glomerulonephritis Kidney Transplant Recipient Cohort: A Prospective Multicenter Observational Study

Sponsor: AstraZeneca

View on ClinicalTrials.gov

Summary

This is a prospective observational study aimed at establishing a prospective observational cohort of patients with a confirmed diagnosis of glomerulonephritis (GN) before kidney transplantation in China. Information will be collected on the epidemiology of GN recurrence after kidney transplantation, as well as the outcomes and treatment of the primary disease following kidney transplantation, to provide evidence for subsequent clinical studies, drug development, and translational research. Approximately 300 patients with a confirmed diagnosis of GN before transplantation will be prospectively enrolled. Clinical data will be collected during screening, kidney transplantation, and a 3-year post-transplant follow-up. The frequency of follow-up visits is every 3 months in the 1st year after transplantation, and every 6 months during the 2nd to 3rd years, with a total of 8 follow-up visits. The study will be conducted at 10 sites across China.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

300

Start Date

2026-10-01

Completion Date

2030-08-29

Last Updated

2026-10-21

Healthy Volunteers

No

Locations (9)

Research Site

Beijing, Beijing Municipality, China

Research Site

Guangzhou, Guangdong, China

Research Site

Nanning, Guangxi, China

Research Site

Zhengzhou, Henan, China

Research Site

Wuhan, Hubei, China

Research Site

Yantai, Shandong, China

Research Site

Shanghai, Shanghai Municipality, China

Research Site

Taiyuan, Shanxi, China

Research Cite

Tianjin, Tianjin Municipality, China