Clinical Research Directory

Clinical Outcomes of Magnesium Sulfate in Cervical Interlaminar Epidural Steroid Injection

Sponsor: Marmara University

Summary

This single-center observational comparative cohort study evaluates clinical outcomes following two cervical interlaminar epidural steroid injection protocols used in routine care for chronic cervical radicular pain due to cervical disc herniation. Patients underwent the procedure between January 1 and July 1, 2026 and were classified according to the injectate already administered: lidocaine, dexamethasone, and normal saline, or lidocaine, dexamethasone, and magnesium sulfate. Treatment selection was determined by the treating physician during routine clinical care and was not assigned by the investigators. Data available at ethics approval were obtained retrospectively from clinical records. For patients whose scheduled routine follow-up had not yet occurred, follow-up outcomes were recorded prospectively after ethics approval. No research-specific treatment, additional visit, additional test, or modification of routine care was undertaken. Pain, neck-related disability, and health-related quality of life were evaluated using the Numeric Rating Scale, Neck Disability Index, and Short Form-12 over three months.

Official title: Clinical Outcomes of Magnesium Sulfate Use in Cervical Interlaminar Epidural Steroid Injection for Chronic Cervical Radicular Pain: A Comparative Observational Cohort Study

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