Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
Sponsor: Eli Lilly and Company
Summary
This study will evaluate the efficacy and safety of orforglipron in participants with overweight and assess whether it helps reduce the future risk of obesity-related conditions, including type 2 diabetes, hypertension, and dyslipidemia, and progression to class 1 obesity.
Official title: A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Investigate the Efficacy and Safety of Once-Daily Oral Orforglipron Compared With Placebo in Individuals With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
2001
Start Date
2026-08-26
Completion Date
2030-09
Last Updated
2026-10-08
Healthy Volunteers
No
Interventions
Orforglipron
Administered orally
Placebo
Administered orally
Locations (180)
Pinnacle Research Group, LLC
Anniston, Alabama, United States
Central Research Associates
Birmingham, Alabama, United States
Cahaba Research - Pelham
Pelham, Alabama, United States
Care Access - 801 South Power Road, Mesa
Mesa, Arizona, United States
Absolute Clinical Research
Phoenix, Arizona, United States
Synexus Clinical Research US, Inc./Orange Grove Family Practice
Tucson, Arizona, United States
Orange County Research Center
Lake Forest, California, United States
Healthy Brain Clinic
Long Beach, California, United States
Los Angeles Institute for Metabolic Research
Los Angeles, California, United States
Desert Oasis Healthcare Medical Group
Palm Springs, California, United States
Artemis Institute for Clinical Research
Riverside, California, United States
Riverside Clinical
Riverside, California, United States
Headlands Research- Sacramento
Sacramento, California, United States
Norcal Endocrinology & Internal Medicine
San Ramon, California, United States
Diablo Clinical Research, Inc.
Walnut Creek, California, United States
Yale University School of Medicine
New Haven, Connecticut, United States
Chase Medical Research, LLC
Waterbury, Connecticut, United States
Excel Medical Clinical Trials
Boca Raton, Florida, United States
Flourish Research Acquisition, LLC dba Flourish Research - North Miami
Miami, Florida, United States
New Age Medical Research Corporation
Miami, Florida, United States
Renstar Medical Research
Ocala, Florida, United States
Headlands Research Orlando
Orlando, Florida, United States
Oviedo Medical Research
Oviedo, Florida, United States
Care Access - St. Petersburg
St. Petersburg, Florida, United States
Precision Clinical Research
Sunrise, Florida, United States
SKY Clinical Research Network Group-Brown
Atlanta, Georgia, United States
HOPE Clinical Research & Wellness
Conyers, Georgia, United States
Care Access - Dalton Walmart
Dalton, Georgia, United States
Care Access - Decatur
Decatur, Georgia, United States
Family First Medical Center
Idaho Falls, Idaho, United States
Solaris Clinical Research
Meridian, Idaho, United States
Great Lakes Clinical Trials - Ravenswood
Chicago, Illinois, United States
Iowa Diabetes and Endocrinology Research Center
West Des Moines, Iowa, United States
Cotton O'Neil Clinical Research Center
Topeka, Kansas, United States
Monroe Biomedical Research - Louisville
Louisville, Kentucky, United States
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States
IMA Clinical Research Monroe-Main
Monroe, Louisiana, United States
Centennial Medical Group
Columbia, Maryland, United States
Brigham and Women's Hospital Diabetes Program
Boston, Massachusetts, United States
Great Lakes Research Group, Inc.
Bay City, Michigan, United States
Great Lakes Research Institute
Southfield, Michigan, United States
Arcturus Healthcare , PLC, Troy Internal Medicine Research Division
Troy, Michigan, United States
Headlands Research-Twin Cities
Maplewood, Minnesota, United States
Clinvest Headlands Llc
Springfield, Missouri, United States
M3 Wake Research - Las Vegas Cimarron
Las Vegas, Nevada, United States
Renascor Clinical Research
Reno, Nevada, United States
IMA Clinical Research Warren
Warren Township, New Jersey, United States
Drug Trials America
Hartsdale, New York, United States
NYC Research INC
Long Island City, New York, United States
Rochester Clinical Research, LLC
Rochester, New York, United States
Medication Management
Greensboro, North Carolina, United States
Monroe Biomedical Research
Monroe, North Carolina, United States
West Clinical Research
Morehead City, North Carolina, United States
Trial Management Associates - Wilmington - Floral Parkway
Wilmington, North Carolina, United States
Lillestol Research
Fargo, North Dakota, United States
Remington-Davis, Inc
Columbus, Ohio, United States
Central States Research
Tulsa, Oklahoma, United States
The Corvallis Clinic, P.C.
Corvallis, Oregon, United States
Clinical Renal Associates Ltd.
Media, Pennsylvania, United States
Suburban Research Associates
West Chester, Pennsylvania, United States
Care Access - Mauldin
Mauldin, South Carolina, United States
New Phase Research and Development
Knoxville, Tennessee, United States
Clinical Research Associates Inc
Nashville, Tennessee, United States
IMA Clinical Research Austin
Austin, Texas, United States
Headlands Horizons, LLC dba Headlands Research-Brownsville
Brownsville, Texas, United States
Cedar Health Research - Texas Native Health
Dallas, Texas, United States
Headlands Research-El Paso
El Paso, Texas, United States
Cedar Health Research - Euless
Euless, Texas, United States
Biopharma Informatic, LLC
Houston, Texas, United States
Care Access - Houston - Clinical Trials Center by Walmart & Care Access
Houston, Texas, United States
Activian Clinical Research
Kingwood, Texas, United States
DCOL Center for Clinical Research
Longview, Texas, United States
IMA Clinical Research San Antonio
San Antonio, Texas, United States
VIP Trials
San Antonio, Texas, United States
Consano Clinical Research, LLC
Shavano Park, Texas, United States
Care Access - Tyler - Clinical Trials Center by Walmart & Care Access
Tyler, Texas, United States
Sovah Clinical Research-River District
Danville, Virginia, United States
Clinical Research Partners, LLC
Richmond, Virginia, United States
CAMC Institute for Academic Medicine
Charleston, West Virginia, United States
Frontier Clinical Research, LLC
Kingwood, West Virginia, United States
CONEXA Investigacion Clinica S.A.
Buenos Aires, Argentina
CIPREC
Buenos Aires, Argentina
CARDIAMET Investigaciones Médicas
Buenos Aires, Argentina
Investigaciones Medicas Imoba Srl
Buenos Aires, Argentina
Centro Médico Viamonte
Buenos Aires, Argentina
CEMEDIC
Buenos Aires, Argentina
Fundación Respirar
Buenos Aires, Argentina
Instituto Centenario
CABA, Argentina
IDIM - Instituto de Investigaciones Metabólicas
Ciudad de Buenos Aires, Argentina
Sanatorio Esperanza
Esperanza, Argentina
Centro Diagnóstico Bioimagenes
Lanus, Argentina
Centro de Investigaciones Médicas Mar del Plata
Mar del Plata, Argentina
Instituto de Cardiología Wolff
Mendoza, Argentina
Instituto Especialidades de la Salud Rosario
Rosario, Argentina
Instituto de Investigaciones Clinicas Rosario
Rosario, Argentina
CardioAlem Investigaciones
San Isidro, Argentina
Instituto Médico de Alta Complejidad San Isidro Sa
San Isidro, Argentina
Centro de Investigaciones Médicas Tucuman
SAN M. de Tucuman, Argentina
Instituto de Investigaciones Clínicas San Nicolas
San Nicolás de los Arroyos, Argentina
Centro de Investigaciones Clinicas del Litoral
Santa Fe, Argentina