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NOT YET RECRUITING
NCT07856693
NA

Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes

Sponsor: University of Zagreb

View on ClinicalTrials.gov

Summary

After tooth extraction, the surrounding bone and soft tissue may undergo dimensional reduction. Socket preservation involves placement of a bone graft into the extraction socket and coverage with a membrane to support healing before dental implant placement. This study will compare two membranes used with the same allogeneic bone graft. One group will receive a resorbable magnesium membrane (NOVAMag), and the other group will receive a non-resorbable polytetrafluoroethylene membrane (permamem). Participants requiring tooth extraction followed by implant placement will be randomly assigned to one of the two groups. Extraction and grafting procedures will be standardized. Follow-up examinations will take place 7 days, 21 days, and 3 months after socket preservation. Soft tissue healing and postoperative complications will be assessed. Cone-beam computed tomography (CBCT) scans obtained before extraction and at 3 months will be used to evaluate changes in alveolar bone volume. During planned implant placement at 3 months, a bone sample will be collected from the treated site for microscopic examination. The study aims to compare bone and soft tissue healing between the two membrane groups.

Official title: Comparative Evaluation of Bone and Soft Tissue Healing Following Alveolar Socket Preservation Using Maxgraft Plus With NOVAMag and Permamem Membranes

Key Details

Gender

All

Age Range

25 Years - Any

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2026-11-01

Completion Date

2028-07-31

Last Updated

2026-10-07

Healthy Volunteers

Yes

Interventions

DEVICE

NOVAMag Membrane

Placement of a resorbable magnesium barrier membrane over the grafted extraction socket during alveolar socket preservation.

DEVICE

permamem Membrane

Placement of a non-resorbable polytetrafluoroethylene barrier membrane over the grafted extraction socket during alveolar socket preservation.

PROCEDURE

Alveolar Socket Preservation With an Allogeneic Bone Graft

Atraumatic tooth extraction, socket debridement, and saline irrigation, followed by placement of an allogeneic bone graft. The grafted socket will be covered with the membrane assigned to the participant's treatment group.

Locations (1)

School of Dental Medicine

Zagreb, City of Zagreb, Croatia