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Summary
Effective ventilation during cardiopulmonary resuscitation is essential but can be difficult to achieve consistently. Current practice relies on visible chest rise to guide ventilation volume, although this may not always accurately reflect the actual volume of air delivered. This study aims to determine whether a real-time ventilation feedback device, providing objective information on ventilation volume and air leakage, improves adherence to recommended ventilation volumes compared with standard ventilation without feedback. The study will focus on patients receiving CPR with a supraglottic airway and synchronous ventilation.
Official title: The OXY-VENT Study: an Investigator-initiated, Single-center, Parallel-group, Randomized Controlled Superiority Trial of Real-time Ventilation Feedback Versus Control to Improve Ventilation Quality in Adults With Out-of-hospital Cardiac Arrest.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
515
Start Date
2027-01-01
Completion Date
2028-09-01
Last Updated
2026-10-27
Healthy Volunteers
No
Interventions
Ventilation Feedback Device (Active)
The same flow sensor and device measure inspiratory and expiratory tidal volume, leakage, and ventilation timing, connected between the resuscitator bag and airway device. In feedback mode, the device displays real-time visual feedback to guide the provider toward a target expiratory tidal volume of 400-500 mL.
Control (Recording-Only)
A ventilation feedback device integrated into standard resuscitation equipment, used during out-of-hospital cardiac arrest. The device measures inspiratory and expiratory tidal volume, leakage, and ventilation timing via a flow sensor connected between the resuscitator bag and airway device. In this arm, the device is randomly initiated in recording-only mode, recording the same ventilation parameters without displaying any feedback to the provider.
Locations (1)
RAVU
Bilthoven, Netherlands