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AI-Personalized Skincare Regimen for Facial Photoaging in Women
Sponsor: MDalgorithms Inc.
Summary
The goal of this clinical study was to learn whether a skincare regimen personalized by an artificial intelligence (AI) skin-analysis tool improves signs of facial skin aging in women aged 35 to 65 with mild-to-moderate facial photoaging. The main questions it aimed to answer were: Does the personalized regimen improve fine lines, wrinkles, firmness, smoothness, tone and other signs of skin aging after 4 and 12 weeks of use? Is the regimen well tolerated? Participants completed an online skin questionnaire and uploaded a facial selfie, and the AI tool assigned one of three night creams. Each participant then used a personalized kit at home for 12 weeks: a vitamin C serum and SPF 30 sunscreen in the morning; the assigned night cream (0.3% retinol, 0.6% retinol, or bakuchiol, each with a triple-peptide complex), an eye cream, and a dark spot remover in the evening; and a daily oral marine collagen supplement. Participants visited the clinic at baseline, week 4 and week 12 for expert skin grading, skin measurements, photographs and questionnaires.
Official title: A Clinical Study to Assess the Efficacy of a Customized Skincare Regimen on Women Exhibiting Signs of Skin Aging
Key Details
Gender
FEMALE
Age Range
35 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
43
Start Date
2025-09-30
Completion Date
2026-02-13
Last Updated
2026-10-19
Healthy Volunteers
Yes
Conditions
Interventions
AI-personalized skin longevity regimen
Multi-product topical and oral regimen used at home for 12 weeks, personalized by a proprietary AI analysis of an online questionnaire and facial selfie. Morning: 10% tetrahexyldecyl ascorbate vitamin C serum and SPF 30 sunscreen. Evening: AI-assigned night cream - Cream A (0.3% retinol), Cream B (0.6% retinol) or Cream C (bakuchiol), each with the SenoP3 triple-peptide complex (copper tripeptide-1, palmitoyl tripeptide-38, acetyl hexapeptide-8) - plus an eye cream with SenoP3 and a dark spot remover as needed. Daily: oral wild-caught marine collagen supplement (type I collagen peptides).
Locations (1)
SGS North America Inc., Clinical Research
Richardson, Texas, United States